研究之中，找到我們是誰 | 中央研究院（2025年版形象影片）
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The 75th Lindau Nobel Laureate Meeting will take place from June 28 to July 3, 2026, in Lindau, Germany. Approximately 75 Nobel Laureates and more than 630 young scientists from 88 countries have been invited to participate in this unique forum for face-to-face exchange. Representing Taiwan, two postdoctoral researchers from Academia Sinica—Dr. Shuvadeep Kamarkar of the Institute of Physics and Dr. Yu-Han Huang of the Research Center for Applied Sciences—have been selected to attend after successfully completing a rigorous multi-stage international selection process.
Academia Sinica held a welcome and farewell tea reception for the incoming and outgoing Vice Presidents today (June 22), presided over by President Chien-Jen Chen. President Chen announced that Academician Mei-Yin Chou, Distinguished Research Fellow at the Institute of Atomic and Molecular Sciences; Academician Yi-Fang Tsay, Distinguished Research Fellow at the Institute of Molecular Biology; and Academician Shin-Kun Peng, Distinguished Research Fellow at the Institute of Economics, will serve as Vice Presidents of Academia Sinica. Former Vice President and Academician Tang K. Tang stepped down from the position.
Academia Sinica held its presidential handover ceremony today (June 18), with Academician Chen Chien-Jen assuming office as the 13th President of Academia Sinica from President James C. Liao. Vice President Hsiao Bi-Khim presided over the ceremony, and former President Tsai Ing-wen was invited to attend. Former President Lee Yuan-Tseh, Academia Sinica academicians, colleagues, and distinguished guests from the academic and research communities gathered to witness this important moment of continuity and renewal for Academia Sinica.
Academia Sinica and the National Museum of Natural Science today opened the exhibition Harmony with Geothermal: A Sustainable Dialogue on Humanity, Resources, and Environment in Taichung. The exhibition introduces the science behind geothermal energy and showcases research findings from Academia Sinica’s geothermal team. Visitors can explore how geothermal resources are formed, how they circulate and are stored underground, and how geological analysis can help identify geothermal potential for renewable power generation. The exhibition also encourages reflection on how science can help society balance energy demands, environmental constraints, and local livelihoods in the pursuit of sustainable development.
Academia Sinica, Kyoto University (KU), and the University of California, Los Angeles (UCLA) are jointly holding a trilateral symposium from May 18 to 20, 2026. Following the inaugural symposium in Los Angeles in 2025, this year’s event has moved to Taipei, bringing together leading scholars from the three institutions to focus on new materials and renewable energy, biomedicine and human health, plant and microbial research, and agricultural development. Through active dialogue and interdisciplinary collaboration, the symposium aims to advance the translation of scientific discoveries into concrete solutions for the sustainable development.
In celebration of International Museum Day on May 18, the Academia Sinica Center for Digital Cultures (ASCDC) is launching a new digital project, “The Universal Summons,” on the Open Museum platform this year. Inspired by fantasy worlds, the event combines generative AI and interactive design to create an immersive digital experience. Users can choose different “elemental symbols” to begin personalized exploration through the museum platform, traveling through diverse themes ranging from ancient civilizations to natural ecosystems.
The American Philosophical Society (APS) recently announced its 2026 class of new members. Academia Sinica President James C. Liao has been elected to the Class of Mathematical and Physical Sciences, becoming one of the few international scholars selected this year. APS elects no more than 10 scientists worldwide each year in this class, underscoring the distinction and significance of this honor. Election to the APS recognizes outstanding scientific achievements, intellectual contributions to the world, original insights into the philosophy of science, and their positive impact on society.
Academia Sinica’s Taiwan Bridges Program welcomed its tenth lecture yesterday (April 23), featuring Professor Takaaki Kajita, recipient of the 2015 Nobel Prize in Physics and Professor at the Institute for Cosmic Ray Research, the University of Tokyo. Speaking on “International Collaboration in Basic Science: From My Experience,” Professor Kajita shared how science can transcend national and cultural boundaries to promote understanding and cooperation. Drawing on examples from neutrinos and gravitational waves, he illustrated how humanity continues to expand the frontiers of our understanding of the universe.
Quantum Processing Units (QPUs) are the core of superconducting quantum computers. Academia Sinica is actively advancing scalable and reliable fabrication technologies for superconducting QPUs. A key step toward this goal is the implementation of high-throughput, iterative testing on large-scale QPUs. To overcome the limitations of traditional calibration methods, Academia Sinica has recently collaborated with NVIDIA to leverage the NVIDIA Ising family of AI models, developing AI-driven automated calibration technologies. This approach significantly improves testing efficiency and system scalability, laying the foundation for large-scale quantum chip development.
The ninth lecture in Academia Sinica’s TAIWAN BRIDGES program was held yesterday (April 7), featuring Professor Kurt Wüthrich, recipient of the 2002 Nobel Prize in Chemistry. In his lecture, titled “The Molecules of Life, AI and Human Health,” Professor Wüthrich shared the technological breakthroughs that enabled the use of nuclear magnetic resonance (NMR) to determine the structures of biological molecules, as well as the application of these advances in precision medicine. He also noted that amid the rapid rise of artificial intelligence (AI) and accelerating technological change, the ability to keep learning and adapting has become an essential quality. The event drew a full house, with more than 400 researchers and students in attendance.
The eighth lecture in Academia Sinica’s TAIWAN BRIDGES program featured Professor Edvard I. Moser of the Norwegian University of Science and Technology, recipient of the 2014 Nobel Prize in Physiology or Medicine. In his lecture, titled “The Brain’s GPS: How We Know Where We Are,” Professor Moser explored the mysteries of how the brain constructs its system for spatial cognition.
Achieving net-zero emissions is a key priority and widely anticipated by Taiwanese society. How to accelerate the broad application of scientific research to society and enhance human well-being has become an important challenge in the next phase of net-zero research. Academia Sinica, in collaboration with the Stanford Doerr School of Sustainability, has for the first time organized the “2026 Net-Zero Technology Business Plan Competition.” Stanford students developed commercialization proposals based on Academia Sinica’s net-zero technologies, using Taiwan’s energy transition as the context. The final round was held today (March 27) at Academia Sinica. All teams performed exceptionally well and were closely matched. Ultimately, CorePower and Century EGS were jointly awarded first place.
Department of International Affairs
2026/06/17
Academia Sinica and National University of Science and Technology, Oman Sign MoU to Strengthen Academic and Research Collaboration
Institute of Atomic and Molecular Sciences
2026/06/15
Call for Proposals: The 2026 iMATE program is now open for public solicitation
Department of Academic Affairs and Instrument Service
2026/06/01
2026 IRB-BM Training I
2026/05/25
2027 National Taiwan University and Academia Sinica Innovative Joint Program accepting Applications until July 10, 2026
Institute of Modern History
2026/05/22
Dr Kuan-Jen Chen, Assistant Research Fellow at the Institute of Modern History, Elected a Fellow of the Royal Historical Society (FRHistS)
2026/05/21
The 2026 Academia Sinica Fellowships for Doctoral Candidates in the Humanities and Social Sciences
Secretariat
2026/05/13
2026Academia Sinica Cultural Events
2026/05/12
2027 Taipei, Taichung and Kaohsiung Veterans General Hospitals, Tri-Service General Hospital and Academia Sinica Joint Research Program Accepting Applications from June 1 to July 15, 2026
2026/05/04
Call for Proposals: We are currently accepting applications for the 2027 Academia Sinica Biotechnology Research and Translation Program and Infectious Diseases Research Project.
2026/04/27
Knowledge Feast-Popular Science Lecture in Honor of Late President Chia-Hua Chu: “Quantum and Nano Science & Technology for Modern Civilization"
2026/04/16
TAIWAN BRIDGES Lecture by Nobel Laureate: “International Collaboration in Basic Science - From My Experience”
Personnel Office
2026/04/14
Establishment of the Office of Mediation: Creating a New Channel for Secure Communication
Genomics Research Center
2026/04/10
Academician Chien-Jen Chen Awarded the 2026 APASL Okuda-Omata Distinguished Award
2026/03/26
TAIWAN BRIDGES Lecture by Nobel Laureate: “The Molecules of Life, AI and Human Health”
2026/03/12
TAIWAN BRIDGES Lecture by Nobel Laureate: “The Brain’s GPS: How We Know Where We Are”
2026/03/02
Knowledge Feast-Popular Science Lecture in Honor of Late President Shih-Chieh Wang: “Understanding Triadic Balance in a Real-Time Experiment among Taiwanese, Chinese, and Americans”
2026/02/25
We are currently accepting applications for the 2027 Academia Sinica Career Development Award, Investigator Project Grant, Thematic Research Program, and Grand Challenge Program.
2026/02/13
TAIWAN BRIDGES Lecture by Nobel Laureate: “The Antibody Revolution”
2026/02/11
Knowledge Feast-Popular Science Lecture in Honor of Late President Chien Shih-liang: "To Fertilize or Not? — How Plant Nutrition Shapes Our Food and the Environment""
Institute of Ethnology
2026/02/03
FIELD MATERIALS INSTITUTE OF ETHNOLOGY ACADEMIA SINICA Volume 31 has been published
2026/01/30
Academia Sinica Lecture by 2025 Nobel Laureate Dr, John Martinis "Quantum Computing’s Industrial Revolution: From Lab to Fab"
Institute of Chemistry
2026/01/29
Distinguished Research Fellow Yu-Ju Chen of the Institute of Chemistry Receives the HUPO Distinguished Achievement in Proteomic Sciences Award
TAIWAN BRIDGES Lecture by Nobel Laureate: “Why You Should Love GMOs?”
2026/01/19
TAIWAN BRIDGES Lecture by Nobel Laureate: “Is There a Planet B – Will Humanity Emigrate to an Exoplanet?”
2026/01/09
TAIWAN BRIDGES Lecture by Nobel Laureate: “The Laser and Quantum Physics”
2025/12/29
The 2026 Academia Sinica Fellowships for Doctoral Candidates in the Humanities and Social Sciences Accepting Applicants
2025/12/23
Knowledge Feast-Popular Science Lecture in Honor of Late President Tsai Yuan-Pei: "You and AI: Thriving with Technology"
ACADEMIA SINICA PRESS
2025/12/22
“Geometry and Light of Knowledge: Selected Buildings of Academia Sinica” has been published
2025/12/18
2025 NSTC Research Fellows Awardee from Academia Sinica
2025/12/10
Public announcement of the revision draft of the “Information and Biospecimen Usage Fees of the Taiwan Biobank”
2025/12/03
Dr. See-Yeun Ting of the Institute of Molecular Biology Selected as EMBO Young Investigator
2025/11/21
The Haptic Eye: Sensory Encounters in VR Cinema
TAIWAN BRIDGES Lecture by Nobel Laureate: “Who Can Influence the End of Conflict-Related Sexual Violence (CRSV) Worldwide? – The Power of Personal Stories and the Role of Activism”
2025/11/05
TAIWAN BRIDGES Lecture by Nobel Laureate: “The End of Disease? – The Extraordinary Developments in Biomedicine and the Implications for Humanity”
2025/11/01
TIGP Application Announcement for 2026
2025/10/29
2025 Academia Sinica Lecture: Black Holes: Where Disciplines Cross
2025/10/08
Academia Sinica at the Frankfurt Book Fair: Opening Global Dialogue Through Diverse Academic Perspectives
Research Center for Critical Issues
2025/09/30
Academia Sinica’s Internally Developed Quantum Computing Test Space Opens for Applications
2025/09/17
Congratulations to Dr. Liang-Yan Hsu on Receiving the 2024 Emerging Investigator Best Paper Award from The Journal of Chemical Physics
2025/09/15
21 Awardees Received Fellowship for Doctoral Students in Humanities and Social Sciences
2025/08/13
Knowledge Feast-Popular Science Lecture in Honor of Late President Ta-You Wu : “Unveiling the Secret of Floral Beauty"
2025/07/23
Academia Sinica Co-hosts Tri-Lateral Biomedical Symposium with UCLA and Kyoto University
2025/07/15
Event: Academia Sinica 13th Presidential Search Forum
2025/07/14
2025 IRB-BM Training II
2025/07/08
The Announcement of 2025 TIGP Admissions
2025/06/23
2025/06/19
2nd Session, 2025_ Short-term Domestic Visiting Scholars to Academia Sinica Approved
2025/06/09
Dr. Kuan-Jen Chen has been awarded the 2024 NASOH John Lyman Book Award in World Naval History
2025/06/06
The 2025 Academia Sinica Fellowships for Doctoral Candidates in the Humanities and Social Sciences
2025/05/29
Announcement of the 2025 2nd Session Academia Sinica Postdoctoral Scholars
2025/05/26
2025 Dr. Hu Shih Memorial Chair Professorship Now Accepting Applications
2025/05/23
Election of Research Staff and Research Specialist Representatives to the 13th Academia Sinica Presidential Search Committee Announcement of Candidates
2025/05/15
Announcement of Approval: 2025-2026 International Cooperation and Exchange Program between Academia Sinica and the Polish Academy of Sciences
2025/04/23
2025 IRB-HS Training II
2025/04/21
Knowledge Feast-Popular Science Lecture in Honor of Late President Chia-Hua Chu : “Viewing the Universe through Black Holes"”
2025/04/18
List of New Research Fellow Representatives to Academia Sinica’s 12th General Assembly
[Call for Proposals] 2026 Sustainability Science Research Program
2025/04/02
Join Our EMBO Training Courses “Telling your Story: Writing a Narrative CV”
2025/03/21
Dr. Han-Chin Wang from the Institute of Cellular and Organismic Biology Awarded the 2024 Li Foundation Heritage Prize
2025/03/20
Election of Research Fellow Representatives to Academia Sinica’s 12th General Assembly
2025/03/13
2025 IRB-HS Training I
2025/03/10
2025 Second Session Short-term Domestic Visiting Scholars is Now Open for Online Application by April 18, 2025.
2025/03/04
2024 NSTC Outstanding Research Award Awardees from Academia Sinica
2025/02/28
2025 TIIP- International Internship Program List of Acceptance Interns
2025/02/27
Knowledge Feast-Popular Science Lecture in Honor of Late President Shih-Chieh Wang: “Understanding the Taiwanese People's Will to Defend: Evidence from Polls”
2024/12/19
Announcement of Approval: 2025-2026 International Cooperation and Exchange Program between Academia Sinica and the Czech Academy of Sciences
2024/12/06
The Awards Ceremony for the 2024 Academia Sinica Early-Career Investigator Research Achievement Award will be held on December 9
2024/03/29
2024 TIIP- International Internship Program List of Acceptance Interns!
Institute of European and American Studies
2024/02/20
ICPSR Registration is open for the 2024 ICPSR Summer Program
2024/01/15
TWAS Elects Academician Li-Chyong Chen as TWAS Member
2023/08/22
Letter from President Liao to Ph.D. Students: Supplemental Stipends for Academia Sinica Ph.D. Students
Central Administrative Office
Letter from President Liao: Policy to Supplement Stipends for Academia Sinica Ph.D. Students
Cross-Divisional Research Center-Biomedical Translation Research Center
臺灣人體生物資料庫
Apply by：2026/06/30
Division of Life Sciences-Institute of Plant and Microbial Biology
【基因體學技術核心】微矩陣及次世代定序實驗室
Division of Life Sciences-Biodiversity Research Center
王慧瑜副研究員研究室
陳昭倫研究員研究室
Division of Life Sciences-Institute of Molecular Biology
Lab for Cell Dynamics
朱修安實驗室
Division of Life Sciences-Institute of Cellular and Organismic Biology
Wong’s Lab
Dr. Han Chin Wang Lab
Dr. Han-Chin Wang Lab
Division of Life Sciences-Genomics Research Center
阮麗蓉老師實驗室 / Dr. Li-Jung Juan
Dr. Shu-Ling Chiu Lab
Division of Mathematics and Physical Sciences-Institute of Earth Sciences
Division of Mathematics and Physical Sciences-Institute of Statistical Science
Division of Humanities and Social Sciences-Research Center for Humanities and Social Sciences
Center for Survey Research
Chih-Horng Kuo lab
台灣小鼠診所
01/10~07/12
09:00 Institute of History and Philology
[Exhibition Info] Approaching National Treasures: Small Marble Sculpture of a Standing Owl
06/15~07/15
09:00 Genomics Research Center
[Registration] 2026 Genomic Epidemiology Workshop (August 10~14)
06/30
10:00 Institute of Chemistry
[IoC] Mapping the Molecular Landscape of Glycosylation: Analytical Advances and Biomedical Applications
10:00 Institutum Iurisprudentiae
Who Defines the Best Interests of the Child? Conflicts Among Institutional Logics and Interprofessional Collaboration in the Child Sexual Exploitation Protection System
10:00 Genomics Research Center
GRC Seminar: Living in the World of RNA Therapeutics: Past, Present and Future
11:00 Institute of Molecular Biology
Genome Content Switch Fuels Cell-to-Tumor Transition
11:00 Institute of Biomedical Sciences
A Variance‑Regulating microRNA Defines Exceptional Responders and Limits DNA‑Repair Plasticity in Glioblastoma
11:00 Agricultural Biotechnology Research Center
Bridging Genotype and Phenotype through Proteoform-Resolved Top-Down Proteomics
14:00 Institute of Political Science
IPSAS Lecture Series: Beyond Absolute Obedience: Confucian Paternalistic Gratitude in Taiwan.
15:00 Institute of History and Philology
Traversing Eurasia and Cruising the Seas: Objects of Chinese Art in European Collections
07/01
13:00 Agricultural Biotechnology Research Center
A transcriptional module for auxin-mediated floral initiation
14:00 Institute of Physics
【2026 Symposium of Newly Elected Academicians】Quantum Materials and Nanoscience for the Advancement of Next Generation Quantum and Chip Technologies
A research team led by Professor Shang-Te Danny Hsu at the Institute of Biological Chemistry, Academia Sinica, combined advanced methyl NMR, protein dynamics analysis, and molecular simulations to map, for the first time, the long-range allosteric regulatory network inside the important tumor suppressor protein BAP1 and to systematically examine the molecular effects of nearly 50 cancer-related mutations. BAP1 is closely linked to several cancers, including mesothelioma, uveal melanoma, and renal cell carcinoma, and its core structure has a rare deeply knotted fold. The team found that an amino acid in the protein core, L49, acts as a key hub for coordinating internal communication. Even a mutation that shortens its side chain by just one carbon atom can disrupt the dynamic coupling between different parts of the protein, causing its deubiquitinase activity to be lost. Further analysis showed that many cancer mutations found in patients are far from the active site, yet they can still affect protein stability and function by disturbing this regulatory network. This study provides one of the most comprehensive structure-function maps of BAP1 cancer mutations to date, offering an important molecular basis for understanding how BAP1-related cancers develop and highlighting the unique power of advanced NMR techniques for revealing protein dynamics and disease mechanisms.
Before cell division, DNA must be accurately replicated. At the same time, many genes continue to be actively transcribed. When the DNA replication machinery encounters the transcription machinery on the same genomic region, transcription–replication conflicts (TRCs) can arise, leading to replication fork stalling, DNA damage, and genome instability. How cells ensure efficient DNA replication through highly transcribed regions therefore represents a fundamental question in genome stability research.
Microscale neural probes are essential tools for next-generation brain-computer interfaces, but inserting them into the brain can injure tissue and blood vessels. In this study, Dr. Yu-Wei Wu’s team at the Institute of Molecular Biology, Academia Sinica, together with collaborators at Stanford University, combined ultrasensitive force measurement with real-time live imaging to observe how probes of different diameters enter and impact the mouse brain.
The newest issue of the Journal of Social Sciences and Philosophy has just been published by the Research Center for Humanities and Social Sciences
Monolayer two-dimensional transition metal dichalcogenides offer strong excitonic responses and gate-tunable optical properties, making them attractive for next-generation photonic and optoelectronic devices. However, achieving wafer-scale, room-temperature operation with a high photoluminescence modulation depth remains a key challenge owing to the limited electrostatic control and inefficient light–matter coupling. To address this challenge, an international research team led by Dr. Yu-Jung Lu at the Research Center of Applied Sciences, Academia Sinica, in collaboration with Prof. Vincent Tung’s team at the University of Tokyo, has successfully integrated large-area monolayer molybdenum disulfide (MoS2), a two-dimensional semiconductor, with an atomically smooth hafnium nitride plasmonic back-gate electrode. This work establishes a new active tunable light-emitting platform for two-dimensional materials that operates at room temperature.
Influenza A and B pose equal threats, yet research on type B has long lagged behind. Its dual-lineage nature frequently causes vaccine mismatches, making it a pressing public health concern. Recently, a collaborative research team led by Dr. Che Alex Ma (Genomics Research Center, Academia Sinica) and Dr. Kuan-Ying Huang (National Taiwan University Hospital) has successfully isolated broadly neutralizing antibodies (bnAbs) capable of targeting both Victoria and Yamagata lineages of the influenza B virus.
Cancer cells utilize the alternative lengthening of telomeres (ALT) mechanism to maintain telomere length, bypass cellular senescence, and achieve replicative immortality. Researchers led by Associate Research Fellow Dr. Liuh-Yow Chen at the Institute of Molecular Biology, Academia Sinica, discovered that orphan nuclear receptors recruit the transcriptional corepressor TRIM28 to telomeres, where it promotes H3K9me3 deposition and facilitates ALT activation. Mechanistically, orphan nuclear receptors recruit TRIM28 to telomeric chromatin through protein–protein interactions, thereby facilitating heterochromatin remodeling and functionally linking chromatin reorganization to ALT activation. These findings highlight the essential role of TRIM28-mediated heterochromatin formation in immortalized cells.
The issue contains 3 articles and 1 book review
Cephalochordates, commonly known as amphioxus or lancelets, are widely utilized by the scientific community as model organisms to investigate the ancestral traits of vertebrates. An international research team—including Research Fellow Jr-Kai Yu and Postdoctoral Fellow Che-Yi Lin from the Institute of Cellular and Organismic Biology at Academia Sinica, together with researchers from the USA, South Korea, and China— has sequenced the chromosome-scale genome of Asymmetron lucayanum, a tiny marine animal representing the earliest branch of the cephalochordate lineage. This new genome assembly provides a crucial link in understanding the evolutionary transition from simple invertebrates to complex vertebrates, including humans. Comparative genomic analysis reveals that the Asymmetron genome is significantly larger than those of species within the genus Branchiostoma, which have been the primary focus of previous amphioxus research. The team discovered that this genome expansion was driven by the massive accumulation of "jumping genes" (transposable elements). Remarkably, despite the presence of this extra DNA, the researchers found that the overall gene order—or macro-synteny—has remained incredibly intact over hundreds of millions of years. This stability is likely maintained by selective constraints, potentially due to the necessity for these genes to be co-expressed during development.
Utilizing liposomes for drug delivery is a vital technology in modern nanomedicine. Equipping liposome surfaces with peptides as trigger-responsive release units enables smart, precision-controlled drug delivery. However, peptide–membrane interactions have largely been studied as separate entities ("binary systems"). When membrane-active peptides are directly conjugated onto liposomes ("unary systems"), the constructs often become highly unstable, causing premature drug leakage—an enduring bottleneck in the field.
Cases of ovarian clear cell carcinomas (OCCC) with wild-type ARID1A gene are chemo-resistant and currently lack specific therapies. We identified circadian gene BMAL2 as a critical oncogene that promotes OCCC tumorigenesis by preventing endogenous DNA damage.
We are pleased to announce the new publication of issue 27.2 of Language and Linguistics
The bi-weekly “Academia Sinica Newsletter”(English version) is responsible for sharing professional knowledge, research results and other information in order to keep you abreast of the latest news at Academia Sinica.
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