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My lab at the Institute of Molecular Biology (IMB), Academia Sinica, focuses on the rapid evolution of essential genes and chromosome structures. We are particularly interested in the paradox of how genes and chromosomal features critical for survival and reproduction, typically expected to be evolutionarily conserved, can instead evolve rapidly under strong positive selection. To investigate this, we integrate genetics, genomics, and cytology to uncover the causes and consequences of this phenomenon.

We are seeking 1 postdoctoral researcher to conduct and lead research projects. Candidates will earn authorship on resulting publications and will be strongly encouraged to develop and lead independent projects. Successful candidates will have opportunities to attend international conferences and visit collaborator labs in US or Canada. I’m strongly committed to supporting career development and mentorship for all team members.

Responsibilities:

Lead and contribute to research projects, including international collaborations
Draft and revise manuscripts for publication; assist in grant writing
Develop and pursue independent research directions
Mentor junior lab members
Present data at lab meetings and provide regular project updates
Maintain weekly progress reports on experiments and analysis

Research Topic: How glutamate and glutamine regulate plant growth and defense
Research Description:
Our laboratory uses molecular genetics approaches to study how plants sense and respond to
amino acids (glutamate and glutamine). We have discovered that, in addition to being essential
nutrients for plant growth, glutamate and glutamine can also enhance plant immune responses.
We welcome postdoctoral researchers with independent research capabilities to join us in
exploring the novel functions of amino acids in plants.
All postdoctoral researchers are welcome to take the research topics, materials, and any other
related projects they worked on during their time in our lab to continue developing them in the
next stage of their academic careers, such as in faculty or independent research positions.

Research Topic: How glutamate and glutamine regulate plant growth and defense
Research Description:
Our laboratory uses molecular genetics approaches to study how plants sense and
respond to amino acids (glutamate and glutamine). We have found that, in addition to
being essential nutrients for plant growth, glutamate and glutamine can also enhance
plant defense responses. We welcome individuals who are interested in plant biology
and plan to pursue advanced degrees to join our team in exploring the novel functions
of amino acids in plants.

想將你的專業知識，應用在新藥研發與代謝研究領域嗎？
歡迎加入我們的 NMR 核心設施團隊，成為推動藥物分析及科學突破的重要一員！

1. 操作先進 NMR 儀器，負責代謝物、小分子等樣品之光譜收集、數據分析及研究，協助揭示化合物的結構奧秘。
2. 與醫院實驗室緊密合作，整合各類實驗數據，為精準醫療提供更完整的分析解決方案。
3. 協助整理研究數據，撰寫成果報告、簡報或發表內容，為團隊提供專業且精準的技術支持。
4. 協助儀器的日常維護與檢測，以及核心設施的行政支援工作，確保核心穩定運作。

加入我們，除了能接觸最先進的科學儀器，也將成為新藥研究、謝體學及多元領域分析的關鍵高手，與我們一起探索化學及醫學世界的無限可能！

Responsibilities for postdoctoral fellow:
• Leading independent research, design and carrying out well controlled, reproducible experiments which address well-developed hypotheses.
• Work closely with other team members and external collaborators.
• Present progress internally and externally through conferences.
• Writing manuscripts and assisting with grant applications.

Responsibilities for research assistant:
• Collaborating with team members to design and establish various biochemical assays, molecular biological techniques, mouse colony management and assist mouse-based experimental techniques when needed.
• Overseeing day-to-day lab operations, provide administrative support, maintenance of safety standards, restock and purchasing, databases and standard operating procedures, and general organization of the lab.

The Cheung Lab, relocating from the Francis Crick Institute (London, UK) to the Genomics Research Center (GRC), Academia Sinica (Taipei) in August 2025, is seeking highly motivated and creative researchers to join our team. In GRC, you will be joining a group of enthusiastic postdocs and PhD students with diverse expertise in cancer research and metabolism and will have access to state-of-the-art approaches and resources in GRC as well as other AS institutes.

Our goal is to understand how cancer cells communicate with their immediate microenvironment as well as distal host tissues and organs to regulate metabolic stress and redox homeostasis in tumours to facilitate growth and metastasis, focusing on pancreatic cancer (Cheung et al. PNAS 2024, Cheung and Vousden Nat Rev Cancer 2022, Cheung et al. Cancer Cell 2020, Cheung et al. Genes Dev 2016, Cheung et al. Developmental Cell 2013). We employ functional genomics, metabolomics, ex vivo organoid models, animal models of cancer, and single cell sequencing to uncover new mechanisms of disease and therapeutic targets. Our work seeks to reveal novel strategies that target both cancer cells and host tissues, offering a more refined, systemic approach to cancer treatment.

Research Associate Positions at IMB, Academia Sinica (Starting October 2025)
My lab at the Institute of Molecular Biology (IMB), Academia Sinica, focuses on the rapid evolution of essential genes and chromosome structures. We are particularly interested in the paradox of how genes and chromosomal features critical for survival and reproduction, typically expected to be evolutionarily conserved, can instead evolve rapidly under strong positive selection. To investigate this, we integrate genetics, genomics, and cytology to uncover the causes and consequences of this phenomenon.
We are seeking 1–2 highly motivated B.S. or M.S.-level research associates to join the lab and contribute to new and ongoing projects. Successful candidates will have opportunities to co-author publications and are encouraged to lead independent research projects. Based on performance, there will be opportunities to attend international conferences and visit collaborating labs in the U.S. or Canada. I am committed to supporting career development and mentorship for all team members.

Responsibilities:
•Perform basic molecular biology experiments:
oPCR, molecular cloning, DNA and RNA extraction, sequencing
•Assist with lab management:
oMedia preparation, ordering supplies, and equipment maintenance
•Take initiative to lead or contribute to research projects
•Present work in lab meetings and provide weekly updates

本實驗室利用蘚苔為實驗材料，致力於研究陸生植物的外表形態環境適應及其訊號傳遞的演化過程機制。本計畫會用到分子生物、遺傳、基因組編輯、顯微鏡觀察及蛋白純化等技術。歡迎對植物研究工作有熱忱的你加入。
The lab is using moss (Physcomitrium patens) as a model to investigate various developmental biology-related questions in plants. The lab routinely employs techniques such as genetic manipulations, protein expression/purification, and confocal microscopy observation. We encourage those interested in plant biology to be part of the team.
實驗室網站：https://sites.google.com/view/kock-lab/home

ASIAA CASA Development Center (ACDC) is a software team for the ALMA-Taiwan project, focusing on quality software development to boost science productivity. Please check https://cartavis.org to see what we are actively working on. We are looking for one software developer and one computing system manager with enthusiasm and interests in astronomy to join our team.

Launched in September 2022, the Kamino Lab investigates the fundamental principles that govern cellular behavior and information processing. With Keita’s background in physics, our lab integrates diverse approaches, including molecular genetics, theoretical physics, microscopy, and machine learning. We are currently seeking two research assistants with strong backgrounds in related fields and a passion for interdisciplinary research. Potential areas of exploration include, but are not limited to:
- Live-cell analysis of cellular behaviors using advanced microscopy techniques
- Theoretical analysis of cell-signaling dynamics using probability, information theory, and dynamical systems theory
- Image and time-series analysis using advanced statistical methods, including machine learning
- Development of cutting-edge measurement tools in microscopy and microfluidics

【Position description】
The Institute of Statistical Science, Academia Sinica, invites applications for tenure-track positions at the levels of Assistant, Associate, or Full Research Fellow (equivalent to Assistant, Associate, or Full Professor at universities). We seek visionary researchers eager to contribute to our interdisciplinary community. Candidates should bring fresh perspectives to statistics, data science, and related fields such as computer science and artificial intelligence.

【Job description】
Academia Sinica, Taiwan’s most preeminent academic research institution, offers generous research funding, travel support, faculty housing, and other benefits. The Institute of Statistical Science provides a secure and stimulating research environment, with more than 30 faculty members, supportive administrative and IT teams, and many international visiting scholars and academic activities annually. Unlike university faculty, our researchers have the flexibility to choose whether or not to teach.

Launched in September 2022, the Kamino Lab investigates the fundamental principles that govern cellular behavior and information processing. With Keita’s background in physics, our lab integrates diverse approaches, including molecular genetics, theoretical physics, microscopy, and machine learning. We are currently seeking two research assistants with strong backgrounds in related fields and a passion for interdisciplinary research. Potential areas of exploration include, but are not limited to:
- Live-cell analysis of cellular behaviors using advanced microscopy techniques
- Theoretical analysis of cell-signaling dynamics using probability, information theory, and dynamical systems theory
- Image and time-series analysis using advanced statistical methods, including machine learning
- Development of cutting-edge measurement tools in microscopy and microfluidics

醣分子化學合成
Carbohydrate chemical synthesis