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A. Bioinformatics (NGS / Nanopore Data Analysis)

*Participate in data analysis for high-throughput sequencing experiments such as Illumina/Nanopore
*Establish and maintain NGS/ONT data analysis pipelines, including:
-Quality control (QC), alignment, assembly, and variant detection
-Methylation and other modification analyses
*Write and maintain analysis code (Python/R/bash) to automate, ensure reproducibility, and facilitate handover of processes
*Work closely with experimental staff to discuss experimental design and result interpretation

B. Automation & Agent Builder (Laboratory Automation and AI Agents)

*Assist in building and maintaining laboratory automation systems, such as:
*Automated liquid handling platforms and robotic arms.
*Sensor and monitoring systems (temperature, humidity, equipment status, etc.).
*Collaborate with biological researchers to modularize experimental workflows and design reusable automated workflows.
*Develop "experimental assistant"-type AI agents, including:
*Extracting experimental parameters, workflow planning, and error checking through LLM APIs (e.g., GPT).

Integrating various control programs (Python scripts, REST APIs, MQTT, serial communication, TCP/IP, etc.).

Assist the research team in the following synthetic biology and metabolic engineering-related projects:

1.Carbon Capture System Design and Optimization: Use synthetic biology and metabolic biology to design and enhance the efficiency of plant carbon capture pathways.
2.Microbial Engineering and Directed Evolution: Use E. coli as a model to engineer and evolve new carbon-fixation routes, then implement them in plants or cyanobacteria to boost carbon-fixation performance.

Carbon Utilization Conversion: Use novel carbon capture model species to convert the fixed carbon sources into high-value products.

Collaborate with doctoral students and postdoctoral researchers to engage in the following research and technical tasks:

*DNA Sequencing Techniques: Responsible for the operation and management of next-generation sequencing (NGS) and third-generation sequencing (Nanopore) platforms, including sample preparation and sequencing data analysis
*Gene Engineering and Synthetic Biology Applications: Design novel carbon-metabolism pathways and apply laboratory evolution to construct microorganisms capable of converting greenhouse gases.

Artificial Directed Evolution Research: Use E. coli as a model organism to study the role and applications of DNA copy-number diversity in accelerating directed evolution.

• 從事腦機介面或AR/VR/MR的相關研究。
• 提出假設，設計實驗，並進行數據收集。
• 分析電生理訊號（包括但不限於EEG、EMG、EOG、SSVEP、眼球追蹤器等）並彙總發現。
• 撰寫科學論文並發表成果。
• 與其他團隊成員合作，記錄和轉移開發的技術。
• Carry out research in the field of Brain-Computer Interfaces or AR/VR/MR.
• Formulate hypotheses, plan user studies, and carry out data collection.
• Analyze the collected bio-signals (include but not limited to EEG, EMG, EOG, SSVEP, eye-tracker.. ) and summarize the findings.
• Contribute to the design of innovative devices for collecting bio-signals and test them.
• Write scientific papers detailing findings for scientific conferences and journals.
• Cooperate with other team members and business groups on documenting and transferring the developed technologies.”

Our research team is seeking a Postdoctoral Researcher to join us in studying the ecology and evolution of microbial symbiosis in plant–microbe systems. We integrate field ecology, molecular microbiology, and genomic analyses to understand how microbial communities assemble and adapt across hosts and environments. This position is open until filled.
Current research topics
- The effect of host identity on symbiont community assembly
- Ecological genomics of symbionts across co-occuring native plant hosts
- Functional variation in ecologically important traits in faculative symbionts

Job description
- Lead and particiapte in research projects
- Design and conduct experiments and data analyses
- Actively contribute to scientific writing and presentations
- Mentor junior researchers and assist in training activities
- Manage routine laboratory tasks and other assigned duties

Our research team is seeking 1–2 motivated Research Assistants to join us in studying the ecology and evolution of microbial symbiosis in plant–microbe systems. We integrate field ecology, molecular microbiology, and genomic analyses to understand how microbial communities assemble and adapt across hosts and environments. This position is open until filled.
本研究團隊誠徵 1–2 位研究助理，加入我們研究植物–微生物共生系統之生態與演化。研究內容結合田野生態、分子微生物學及基因體分析，探討微生物群落如何在不同宿主與環境中組成與適應。本職缺即日起開放申請，額滿為止。

Current research topics
- The effect of host identity on symbiont community assembly
- Ecological genomics of symbionts across co-occuring native plant hosts
- Functional variation in ecologically important traits in faculative symbionts
目前研究主題：
- 宿主對其共生菌相之影響
- 共生菌在不同植物宿主間的生態基因體學研究
- 兼性共生菌其不同特徵的功能變異

Job description (Tasks are flexibly assigned; not all are required)
- Conduct field sampling, mostly in roadside, urban, and agricultural environments
- Isolate, culture, and maintain rhizobia strains and associated host plants
- Perform microbiological and molecular experiments (e.g., DNA extraction, NGS library preparation, sequencing)
- Design and conduct genomic experiments and analyses
- Perform bioinformatic analyses (e.g., genome assembly, annotation, and phylogenomics)
- Manage routine laboratory tasks and other assigned duties
工作內容（彈性分配，非所有項目皆為必須）：
- 田野採樣（主要於道路、都市綠地及農業環境）
- 共生菌株與宿主植物之分離、培養與維護
- 執行微生物與分子實驗（如 DNA 萃取、NGS 文庫製備與定序）
- 進行生物資訊分析（基因體組裝、註解、系統基因體學等）
- 實驗室日常管理與其他交辦事項

【About Wong’s Lab】
Our lab studies human stem cells to explore the link between cell proliferation and differentiation. We focus on epigenetic mechanisms regulating progenitor cell growth, aiming to create high-quality cells for precision regenerative medicine. Join us to work with passionate researchers in stem cell and developmental biology, leveraging cutting-edge technology and resources at the institute and Academia Sinica.

【About the Positions】
- Develop individual research projects with guidance; support related research tasks.
- Engage in experimental design, analyze data, and provide regular updates on progress.
- Supervise daily laboratory activities, ensuring a productive and well-organized work environment.

• 從事腦機介面或AR/VR/MR的相關研究。
• 提出假設，設計實驗，並進行數據收集。
• 分析電生理訊號（包括但不限於EEG、EMG、EOG、SSVEP、眼球追蹤器等）並彙總發現。
• 撰寫科學論文並發表成果。
• 與其他團隊成員合作，記錄和轉移開發的技術。
• Carry out research in the field of Brain-Computer Interfaces or AR/VR/MR.
• Formulate hypotheses, plan user studies, and carry out data collection.
• Analyze the collected bio-signals (include but not limited to EEG, EMG, EOG, SSVEP, eye-tracker.. ) and summarize the findings.
• Contribute to the design of innovative devices for collecting bio-signals and test them.
• Write scientific papers detailing findings for scientific conferences and journals.
• Cooperate with other team members and business groups on documenting and transferring the developed technologies.”

• 從事腦機介面或AR/VR/MR的相關研究。
• 提出假設，設計實驗，並進行數據收集。
• 分析電生理訊號（包括但不限於EEG、EMG、EOG、SSVEP、眼球追蹤器等）並彙總發現。
• 撰寫科學論文並發表成果。
• 與其他團隊成員合作，記錄和轉移開發的技術。
• Carry out research in the field of Brain-Computer Interfaces or AR/VR/MR.
• Formulate hypotheses, plan user studies, and carry out data collection.
• Analyze the collected bio-signals (include but not limited to EEG, EMG, EOG, SSVEP, eye-tracker.. ) and summarize the findings.
• Contribute to the design of innovative devices for collecting bio-signals and test them.
• Write scientific papers detailing findings for scientific conferences and journals.
• Cooperate with other team members and business groups on documenting and transferring the developed technologies.

本研究團隊致力於探索台灣溫泉與海岸環境中藍綠菌（cyanobacteria）的趨光性分子調控機制，以及其在環境永續應用中的潛力。加入我們，您將有機會參與：解析新穎台灣溫泉藍綠菌株之光訊號傳遞與趨光性路徑, 執行分生、生化、基因體學相關實驗（如基因突變、蛋白質分析、RNA/DNA 操作、菌株培養等）, 協助進行基因體／轉錄體實驗與分析, 參與跨團隊合作研究，包括台灣溫泉微生物多樣性與永續應用等主題, 此職務適合希望在光合作用、微生物生理、與環境永續生物科技領域發展的研究助理。

【About Sakamoto Lab】
What is Life? How do lifeless molecules come together to create dynamic and purposeful living things? The “Laboratory of Designer Life” explores this fundamental question from physics viewpoints by combining experiments and theory. We take a bottom-up approach: instead of studying living cells as they are, we re-build key aspects of life in the lab, piece by piece, using building blocks of life. Our goal is to reveal the core principles underlying the beautiful self-organization of life. We seek people who are motivated to work on:

1. Developing experiments integrating cutting-edge microfabrication, microfluidics, and purified biomolecular systems to reveal novel self-organization phenomena
2. Experimental measurements using microscopes with photo-manipulation systems, energy conversion measurements, and quantitative image & data analysis
3. Theoretical analysis/modeling/simulation using soft matter physics, active matter physics, active gel theory, active nematics

【Research Focus】
Potential areas of exploration include but are not limited to:

1. Biomolecular Self-Organization: Explore to understand how nm-scale biomolecules spontaneously assemble into µm-to-mm-scale larger functional structures without any blueprint by developing innovative bottom-up systems
2. Engineering Life: Designing and building life-like systems that not only mimic but could potentially outperform natural cells, which will open up exciting opportunities in biotechnology and sustainable material development

Please visit our website for more details: https://sites.google.com/as.edu.tw/sakamoto-lab

【What We Offer】
1. Innovative Environment: Work at the forefront of biophysics, active matter physics, bioengineering, and synthetic biology
2. Skill Development: Gain hands-on experience in advanced microfabrication and in vitro protein experimental techniques, scientific writing and presentation skills
3. Collaborative Culture: Join the team that is motivated to develop and share knowledge for mutual growth

The Biodiversity Research Center, Academia Sinica (BRCAS; https://biodiv.tw/index.php?lang=en ), Taipei, Taiwan invites applications for a tenure-track position at the Assistant Research Fellow (equivalent to “assistant professor” at universities) level or above in the field of marine ecology and biodiversity to strengthen the research at the Green Island Marine Research Station.