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【Research Focus】
The Lab for Cell Dynamics (LCD) at Academia Sinica explores the biological functions of large-scale cell death during embryonic development, integrating advanced quantitative and imaging techniques. Our recent work (PMID: 38987590) reveals how developmental signals prime cells for death and how this process might influence aging. We invite passionate junior scientists to join our team to investigate:
1.How developmental cues orchestrate cell death during development.
2.The potential link between developmental death signaling and the aging process.

本實驗室致力於運用分子生物學的方法，研究快速演化的基因與染色體結構。我們對於具有重要功能的基因與染色體結構在演化上理應高度保守，卻仍觀察到快速演化的現象感到好奇，並希望進一步理解背後的機制與演化動力。我們目前的研究發現自私的基因可以解釋部分這些現象。我們的研究將針對這些矛盾現象進行系統性探討，並結合不同層次的實驗方法深入剖析其生物學意涵。 本實驗室將於 2025 年 10 月正式成立，現誠徵博士後助理新實驗室進行主導，並發展獨立研究計畫，並有機會參與論文發表並獲得作者資格。我將會視情況提供參與國際研討會或參與國外合作者實驗室的機會。我將提供職涯發展的建議及協助。 工作內容： -主導獨立規劃並執行研究計畫 -撰寫論文並協助申請研究計劃 -鼓勵發展獨立研究計劃 -帶領並指導年輕實驗室成員 -參與實驗室會議並定期報告研究進度 -每週更新實驗進展

My lab at the Institute of Molecular Biology (IMB), Academia Sinica, focuses on the rapid evolution of essential genes and chromosome structures. We are particularly interested in the paradox of how genes and chromosomal features critical for survival and reproduction, typically expected to be evolutionarily conserved, can instead evolve rapidly under strong positive selection. To investigate this, we integrate genetics, genomics, and cytology to uncover the causes and consequences of this phenomenon.

We are seeking 1 postdoctoral researcher to conduct and lead research projects. Candidates will earn authorship on resulting publications and will be strongly encouraged to develop and lead independent projects. Successful candidates will have opportunities to attend international conferences and visit collaborator labs in US or Canada. I’m strongly committed to supporting career development and mentorship for all team members.

Responsibilities:

Lead and contribute to research projects, including international collaborations
Draft and revise manuscripts for publication; assist in grant writing
Develop and pursue independent research directions
Mentor junior lab members
Present data at lab meetings and provide regular project updates
Maintain weekly progress reports on experiments and analysis

Research Associate Positions at IMB, Academia Sinica (Starting October 2025)
My lab at the Institute of Molecular Biology (IMB), Academia Sinica, focuses on the rapid evolution of essential genes and chromosome structures. We are particularly interested in the paradox of how genes and chromosomal features critical for survival and reproduction, typically expected to be evolutionarily conserved, can instead evolve rapidly under strong positive selection. To investigate this, we integrate genetics, genomics, and cytology to uncover the causes and consequences of this phenomenon.
We are seeking 1–2 highly motivated B.S. or M.S.-level research associates to join the lab and contribute to new and ongoing projects. Successful candidates will have opportunities to co-author publications and are encouraged to lead independent research projects. Based on performance, there will be opportunities to attend international conferences and visit collaborating labs in the U.S. or Canada. I am committed to supporting career development and mentorship for all team members.

Responsibilities:
•Perform basic molecular biology experiments:
oPCR, molecular cloning, DNA and RNA extraction, sequencing
•Assist with lab management:
oMedia preparation, ordering supplies, and equipment maintenance
•Take initiative to lead or contribute to research projects
•Present work in lab meetings and provide weekly updates

針對臺灣地區一般民眾，執行臺灣人體生物資料庫計畫大台北地區宣導及收案作業。
工作內容包括：計畫宣導、問卷訪談、身體檢測、抽血與檢體處理等。

To perform research on quantum matter theory; more details can be found at https://sites.google.com/view/qmtheory/job-openings.