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This position is ideal for candidates with a background in evolutionary genetics, bioinformatics, and molecular biology who are seeking to expand their hands-on laboratory experience.

Key Responsibilities

*Perform routine microbiology and molecular biology experiments, including PCR, DNA/RNA extraction, and sequencing.
*Assist with lab management, including media preparation, ordering supplies/consumables, and maintaining equipment.
*Encouraged to independently design and execute small-scale research projects.
*Participate in lab meetings and regularly present research progress.
*Provide weekly updates on experimental progress.

We seek for a highly motivated research assistant to join the Marine Evo-Evo-Devo laboratory of Vincent Laudet’s Unit at the ICOB’s Marine Research Station at Yilan (https://groups.oist.jp).

(1) Long-standing research interest in the crosstalk between immune and metabolic signaling, or immunometabolism, and its impact on physiological/pathophysiological processes. Examples of study areas include (but not limited to):
研究免疫和代謝信號之間的相互作用（即免疫代謝）及其對生理/病理過程的影響。
* Immunometabolism in tissue homeostasis (Science 368:eaat3987; J Clin Invest 123:261; Nat Med 18:1665)
* Mitochondrial dynamics in liver metabolism (JCI Insight 7:e150041; Cell Metab 22:709)
* Circadian/metabolic rhythm and metabolites mediated inter-organ communication (Nature 502:550)
* Mitochondrial bioenergetics in inflammatory activation and resolution of immune cells (eLife 9:e54090; Cell Metab 7:485
(2) Studying the effect of gene regulation pathways on adipose tissue metabolism.
研究脂肪細胞代謝與基因訊號相關途徑之影響。
* Preadipocyte IL-13/IL-13R1 signaling regulates beige adipogenesis through modulation of PPAR activity (JCI 135(11):e169152)
(3) Lab Management.
協助實驗室管理（包含：實驗室耗材訂購管理與經費核銷、化學藥品和抗體與引子歸檔、IACUC與IRB文件上傳等…）。
(4) Ad-hoc tasks assigned by supervisor.
主管臨時交辦事項。

林暐翔實驗室招聘學士級助理/碩士級助理。
工作內容為30%基礎實驗工作，70%專題研究計畫 (比例可討論)。基礎工作包括藥品採購，維護儀器，準備 agar plate 跟培養液等。專題研究計畫包括微生物與分生實驗，顯微鏡實驗，微流體培養等。我們特別關注具有分子生物學，微生物學相關研究專長的對象。我們會優先考慮未來想讀碩班或博班的人。
Dr. Wei-Hsiang Lin's lab recruiting Bachelor level/Master level research assistant. Job description: 30% on basic experiments, 70% on scientific project (relative ratio can be adjusted). Basic experiments: ordering reagents, maintaining equipments, prepare agar plate and culture media, etc. Scientific project including microbiology and molecular biology experiments, microscopy, microfluidic culture, etc. We are particularly looking for people with expertise in molecular biology and microbiology. We will prioritize people who want to pursue a master or PhD degree in the future.

研究主題: 麩胺酸與麩醯胺酸如何調控植物的生長與防禦
研究內容: 
本實驗室以分子遺傳的研究方法，探討植物對胺基酸（麩胺酸與麩醯胺酸
）的感應與訊息傳導。我們發現麩胺酸與麩醯胺酸除了是植物生長所必需的營
養成分，也可以促進植物的防禦反應，歡迎對植物學研究有興趣，並準備攻讀
更高學位者加入我們的行列，一起探索植物胺基酸的新功能。
Research Topic: How glutamate and glutamine regulate plant growth and defense
Research Description:
Our laboratory uses molecular genetics approaches to study how plants sense and
respond to amino acids (glutamate and glutamine). We have found that, in addition to
being essential nutrients for plant growth, glutamate and glutamine can also enhance
plant defense responses. We welcome individuals who are interested in plant biology
and plan to pursue advanced degrees to join our team in exploring the novel functions
of amino acids in plants.

The major research interests in the LAI lab are to understand the molecular mechanisms underlying how bacterial pathogens deploy protein secretion systems for survival at its ecological niche and successful infection inside the plant host. We study the mechanistic and biological insights of the two major protein secretion nanomachines, type IV and type VI secretion systems (T4SS and T6SS), in Agrobacterium tumefaciens, the causal agent of crown gall disease and powerful gene transfer tool. We also aim to identify novel agrobacterial and plant genes critical for plant transformation and gene editing. The knowledge may provide new insights to improve Agrobacterium-mediated plant transformation and translational applications in biomedicine and/or agriculture.

The Research Assistant will work with a senior Ph.D. student or a postdoc to carry out a two-year research grant to study the antibacterial T6SS with focuses to investigate the T6SS evolution and assembly mechanisms.

The LAI lab provides the research environments and expertise on studies of protein secretion and pathogen-plant interactions using various tools including genetics/genomics, molecular biology, biochemistry/proteomics, and cell biology. The research may expand to study structural aspects of T6SS-assocaited protein complex using X-ray crystallography and cryoEM. The postdoc is also encouraged to develop an independent project and will be trained to serve as a mentor toward an independent investigator. The LAI lab is also active in international collaborations, which will bring opportunities for abroad training.

針對臺灣地區一般民眾，執行臺灣人體生物資料庫計畫大台北地區宣導及收案作業。
工作內容包括：計畫宣導、問卷訪談、身體檢測、抽血與檢體處理等。

- Assist in studies of neuronal development,
synaptic plasticity, and mechanisms underlying
learning, memory, or sensory functions.
- Depending on expertise and interest, tasks may
include: cell biology, basic biochemistry, imaging,
data analysis, electrophysiology, or mouse
behavioral experiments.
- Support general laboratory operations and
management.

1.研究助理：協助研究或獨立研究。
Research Assistants: Assist in research-related tasks or work on an independent project.
2.博士後研究員：表觀遺傳與轉錄調控於發育及疾病之角色。
Postdoctoral Fellows: Conduct research on the roles of epigenetics and transcriptional regulation in development and diseases.

Responsibility: (either)
(1) Exploring epigenetic control in shaping sexual dimorphic circuit.
(2) Exploring the neural circuit mechanisms through Drosophila olfactory virtual reality system
(3) Exploring circuit integration of thermo-, hygro-, and olfactory sensation.

Highly desirable:
• Metabolomics: Proficiency in Mass Spectrometry or NMR-based metabolic profiling and analysis.
• Systemic Interaction: Experience in studying the Immune System or the Nervous System.
• Expertise in designing and executing complex in vivo experiments. A strong background in developing, breeding, and analyzing genetically modified animal models applied to cancer biology or neuroscience.

Using mouse models and human iPSC system, together with scRNA/ATAC-seq technique to decipher the molecular mechanism for Neurodegeneration and Aging. We also aim to uncover the new method to cure motor neuron disease by gene therapy. We strongly encourage candidates interested in molecular mechanisms of gene regulation as related to non coding RNAs should apply. Candidates experienced in mouse experiments and ESC/iPSC cell culture are preferred, but not required.