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We are seeking 1-2 M.S.-level research associates to join us in dissecting the
mechanisms and consequences of fungal-bacterial competition. We focus on the
interaction between Pseudomonas species and fungal plant pathogens. Using
ecological, functional genomic, and genetic approaches, we aim to determine whether
bacterial defense mechanisms are specific or general against multiple fungi, and vice
versa. Check our lab website: www.labofpie.org
Research topics
1. Functional genomic investigation of fungal or bacterial defense genes
2. Ecology and sampling of Pseudomonas species and interacting fungi in the wild
3. Co-evolutionary consequences of competing fungi and bacteria
Job description:
1. Lead and execute a small-scale independent research project.
2. Present data at the lab meeting and provide weekly research updates
3. Participate in joint lab meetings and journal clubs

This position is ideal for someone who seeks graduate-level training and have strong
interest in microbial ecology and genetics. This position is open until filled

- Assist in studies of neuronal development,
synaptic plasticity, and mechanisms underlying
learning, memory, or sensory functions.
- Depending on expertise and interest, tasks may
include: cell biology, basic biochemistry, imaging,
data analysis, electrophysiology, or mouse
behavioral experiments.
- Support general laboratory operations and
management.

實驗動物飼育管理

研究聚焦於離線RL(Reinforcement Learning)、穩健性RL模型，以及在金融與機器人等真實場域的應用。
主要職責
- 進行 RL 相關研究
- 主導或參與頂尖國際會議／期刊投稿
- 協助撰寫研究計畫並推動產學合作

We seek a highly motivated postdoctoral researcher who wants to push the frontier of sequential decision-making under uncertainty and deploy results in impactful domains.

- Conduct independent and collaborative research on RL
- Co-supervise graduate students and research assistants
- Lead or contribute to top-tier conference/journal submissions
- Assist with grant writing and industry collaborations

1、 協助執行臺灣人體生物資料庫（Taiwan Biobank）各項駐站管理與行政作業。
2、 擔任各合作醫院之聯繫窗口，進行溝通、協調與業務接洽。
3、 協助計畫相關宣導、說明及推廣事務。
4、 協助文件整理、資料建檔及其他行政相關工作。
5、 配合計畫需求，不定期支援全台各地駐站收案相關業務。
6、 其他主管交辦之計畫相關事項。

We are looking to hire experienced mobile developers to help bring the PQConnect project to Android and iOS. PQConnect is a new easy-to-install layer of Internet security. It automatically applies post-quantum cryptography from end to end between computers running PQConnect, adding cryptographic protection to unencrypted applications, working in concert with existing pre-quantum applications to add post-quantum protection, and adding a second application-independent layer of defense to any applications that have begun to incorporate application-specific post-quantum protection. PQConnect works at the network layer similarly to a VPN, but is scalable in ways that most VPN applications are not. You can see more information at https://www.pqconnect.net

1.研究助理：協助研究或獨立研究。
Research Assistants: Assist in research-related tasks or work on an independent project.
2.博士後研究員：表觀遺傳與轉錄調控於發育及疾病之角色。
Postdoctoral Fellows: Conduct research on the roles of epigenetics and transcriptional regulation in development and diseases.

You will assist in exploring the plasticity of sensory cortical neural circuits and their role in the mechanisms of Autism Spectrum Disorders (ASD). The role also includes assisting with routine laboratory administration and management.
1.Research Tools: Two-photon microscopy, functional calcium imaging in awake mice, animal behavioral training, mouse genetics, spatial gene expression, and immunostaining.
Note: This role involves survival surgeries, collection of in vivo samples, and other animal experiments that require the sacrifice of laboratory animals.
2.Responsibilities & Training: conduct experiments under instruction
(1)Technical Training: Mouse handling, image acquisition, data analysis, and mouse behavioral training.
(2)Professional Development:
- Participate in routine lab progress reports and literature reviews.
- Encouraged to participate in internal (at academia sinica) and external symposia, for poster or oral presentations.

Assist the research team in the following synthetic biology and metabolic engineering-related projects:

1.Carbon Capture System Design and Optimization: Use synthetic biology and metabolic biology to design and enhance the efficiency of plant carbon capture pathways.
2.Microbial Engineering and Directed Evolution: Use E. coli as a model to engineer and evolve new carbon-fixation routes, then implement them in plants or cyanobacteria to boost carbon-fixation performance.

Carbon Utilization Conversion: Use novel carbon capture model species to convert the fixed carbon sources into high-value products.

Collaborate with doctoral students and postdoctoral researchers to engage in the following research and technical tasks:

*DNA Sequencing Techniques: Responsible for the operation and management of next-generation sequencing (NGS) and third-generation sequencing (Nanopore) platforms, including sample preparation and sequencing data analysis
*Gene Engineering and Synthetic Biology Applications: Design novel carbon-metabolism pathways and apply laboratory evolution to construct microorganisms capable of converting greenhouse gases.

Artificial Directed Evolution Research: Use E. coli as a model organism to study the role and applications of DNA copy-number diversity in accelerating directed evolution.

[Agrobacterium-mediated transformation]
Research is conducted in a team-based setting. Responsibilities are adjusted according to team members’ background and experience, and relevant training is provided. Tasks involve preparation of Agrobacterium and plant materials, plant infection and transformation experiments, bioinformatics analyses of genomic and transcriptomic data to identify key genes, and molecular genetics approaches to investigate gene functions. For related research projects and recent publications, please see our lab website: https://ipmb.sinica.edu.tw/chkuo/

A. Bioinformatics (NGS / Nanopore Data Analysis)

*Participate in data analysis for high-throughput sequencing experiments such as Illumina/Nanopore
*Establish and maintain NGS/ONT data analysis pipelines, including:
-Quality control (QC), alignment, assembly, and variant detection
-Methylation and other modification analyses
*Write and maintain analysis code (Python/R/bash) to automate, ensure reproducibility, and facilitate handover of processes
*Work closely with experimental staff to discuss experimental design and result interpretation

B. Automation & Agent Builder (Laboratory Automation and AI Agents)

*Assist in building and maintaining laboratory automation systems, such as:
*Automated liquid handling platforms and robotic arms.
*Sensor and monitoring systems (temperature, humidity, equipment status, etc.).
*Collaborate with biological researchers to modularize experimental workflows and design reusable automated workflows.
*Develop "experimental assistant"-type AI agents, including:
*Extracting experimental parameters, workflow planning, and error checking through LLM APIs (e.g., GPT).

Integrating various control programs (Python scripts, REST APIs, MQTT, serial communication, TCP/IP, etc.).