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The Biodiversity Research Center, Academia Sinica (BRCAS; https://biodiv.tw/index.php?lang=en ), Taipei, Taiwan invites applications for a tenure-track position at the Assistant Research Fellow (equivalent to “assistant professor” at universities) level or above in the field of marine ecology and biodiversity to strengthen the research at the Green Island Marine Research Station.

The Biodiversity Research Center at Academia Sinica (BRCAS) invites applications for an innovative scientist specializing in vascular plant research with expertise in one or more of the following areas:
•Plant systematics and taxonomy
•Phylogenetics and evolutionary biology
•Plant ecology and biogeography
•Biodiversity and conservation

The lab of Ka Wai Ma is inviting application working on plant-
microbiota research. The lab is using different model systems and the
associated culture collection to understand the principles governing
plant-microbiota homeostasis. The lab routinely uses omics
techniques including amplicon sequencing, transcriptomics and
reconstitution system. The lab is currently looking for a motivated
candidate to work on a CRISPR editing project. The project aims to
use CRISPR technology to perform gene editing on crops with
subsequent phenotyping.
The position is opened until filled
馬家威實驗室現誠聘研究助理/博士後，從事植物微生物相研究。本實
驗室使用不同的模型系統和相關的微生物庫進行植物微生物相重組實驗
以了解植物微生物群互動平衡機理。實驗室大量使用比如包括擴增子測
序、轉錄組學技術。本實驗室目前正在尋找助理/博士後從事 CRISPR
編輯專案。該專案旨在使用 CRISPR 技術對作物進行基因編輯，並進
行表型分析。

Lab Manager, Genomics Core Facility, Institute of Molecular Biology
Job Description
1.Provide genomics research technical services, including next-generation sequencing (NGS), third-generation sequencing, and spatial transcriptomics experiments (DNA/RNA sample processing, QC analysis, NGS library preparation, new technology development, operation of high-throughput sequencers, qPCR systems, etc.).
2.Customized experimental design, consultation, and development of new technologies.
3.Manage shared instruments and provide training in equipment operation and data analysis.

Core Facility Website https://www.imb.sinica.edu.tw/mdarray/index.html

The Wang lab at the Genomics Research Center (GRC), Academia Sinica in Taipei, is seeking highly motivated and creative researchers to join our team. Our lab focuses on energy metabolism, adipocyte biology, and mitochondrial function, with an emphasis on their roles in metabolic diseases such as obesity, insulin resistance, and non-alcoholic fatty liver disease (NAFLD).
We utilize CRISPR-based functional genomics, small-molecule screening, and mitochondrial biology to uncover novel regulators of brown and beige fat thermogenesis, adipose tissue plasticity, and metabolic homeostasis. Our goal is to develop innovative therapeutic strategies for metabolic disorders.
- Key Research Areas -
* Endothelin 3/EDNRB signaling induces thermogenic differentiation of white adipose tissue. (Nat Commun 2024)
* Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation. (Nat Metab. 2022)
* CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice. (Sci Transl Med. 2020)
* Thermogenic adipocyte biology and metabolic regulation (Nat Rev Endocrinol, 2021)
If you are enthusiastic about metabolism research and aspire to work in an interdisciplinary and collaborative environment, we invite you to apply!

The Wang lab at the Genomics Research Center (GRC), Academia Sinica in Taipei, is seeking highly motivated and creative researchers to join our team. Our lab focuses on energy metabolism, adipocyte biology, and mitochondrial function, with an emphasis on their roles in metabolic diseases such as obesity, insulin resistance, and non-alcoholic fatty liver disease (NAFLD).
We utilize CRISPR-based functional genomics, small-molecule screening, and mitochondrial biology to uncover novel regulators of brown and beige fat thermogenesis, adipose tissue plasticity, and metabolic homeostasis. Our goal is to develop innovative therapeutic strategies for metabolic disorders.
- Key Research Areas -
* Endothelin 3/EDNRB signaling induces thermogenic differentiation of white adipose tissue. (Nat Commun 2024)
* Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation. (Nat Metab. 2022)
* CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice. (Sci Transl Med. 2020)
* Thermogenic adipocyte biology and metabolic regulation (Nat Rev Endocrinol, 2021)
If you are enthusiastic about metabolism research and aspire to work in an interdisciplinary and collaborative environment, we invite you to apply!

1. 執行metagenomics、NGS次世代序列或RNA-sequencing等結果處理及資料分析、統整
2. 執行程式撰寫及相關大數據分析
3. 協助實驗室網頁及相關網路資訊系統管理
4. 協助研究結果彙整與成果報告撰寫
5. 與跨領域學門/實驗室合作，整合及共同分析實驗數據

針對臺灣地區一般民眾，執行臺灣人體生物資料庫計畫大台北地區宣導及收案作業。
工作內容包括：計畫宣導、問卷訪談、身體檢測、抽血與檢體處理等。

針對臺灣地區一般民眾，執行臺灣人體生物資料庫計畫大台中地區宣導及收案作業。
工作內容包括：計畫宣導、問卷訪談、身體檢測、抽血與檢體處理等。

The lab is using moss (Physcomitrium patens) as a model to
investigate various developmental biology-related questions
in plants. The lab routinely employs techniques such as
genetic manipulations, protein expression/purification, and
confocal microscopy observation. We encourage those
interested in plant biology to be part of the team.
實驗室網站：https://sites.google.com/view/kock-lab/home

本實驗室的研究重點為傳染病及癌症新藥研發，利用結構生物學的技術（X光結晶學，低溫電子顯微鏡）探討新冠肺炎，流感，抗藥性細菌感染以及癌細胞之膜蛋白及醣蛋白結構，作為新藥研發的基礎。
1.藉由分析蛋白質的立體空間結構，作為新藥設計的基礎。
2.運用細胞及動物實驗模型，探討新型藥物之廣度及效能。
My lab foucuses on structural biology and drug discovery in infectious diseases and cancers. X-ray crystallography and cryo-EM are being used to study membrane proteins and glycoproteins in SARS-COV-2, influenza viruses, drug-resistant bacteria and cancers, to provide structural basis for drug-discovery and vaccine design. In vitro cell based assays and in vivo animal models are being used to validate the efficacy of novel vaccines.

【工作內容 / Responsibilities】
本實驗室的研究重點為傳染病及癌症新藥研發，利用結構生物學的技術（X光結晶學，低溫電子顯微鏡）探討新冠肺炎，流感，抗藥性細菌感染以及癌細胞之膜蛋白及醣蛋白結構，作為新藥研發的基礎。
1.藉由分析蛋白質的立體空間結構，作為新藥設計的基礎。
2.運用細胞及動物實驗模型，探討新型藥物之廣度及效能。
My lab foucuses on structural biology and drug discovery in infectious diseases and cancers. X-ray crystallography and cryo-EM are being used to study membrane proteins and glycoproteins in SARS-COV-2, influenza viruses, drug-resistant bacteria and cancers, to provide structural basis for drug-discovery and vaccine design. In vitro cell based assays and in vivo animal models are being used to validate the efficacy of novel vaccines.