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We investigate the mechanisms of telomere maintenance in regulating aging and cancer development. We utilize cell biology, mouse models, and next-generation sequencing techniques to explore the role of telomere function in aging-related diseases and cancer. Additionally, by integrating clinical medicine and medicinal chemistry, we aim to understand disease mechanisms and develop therapeutic approaches.

我們正在尋找經驗豐富的行動應用程式開發人員，協助將 PQConnect 專案帶入 Android 和 iOS 作業系統。PQConnect 是一個全新且易於安裝的網路安全層，它能在有運行 PQConnect 的終端之間自動引入端到端的後量子加密技術。同時，它能與採用傳統密碼學的應用程式共同運作，並為任何已經內建後量子加密技術的使用者應用程式額外增加第二層的防護。PQConnect 在網路層的運作方式類似於 VPN，但它可容許的擴展性是大多數 VPN 應用程式所無法比擬的。如需了解更多資訊，請參考： https://www.pqconnect.net

The Institute of Biological Chemistry (IBC) at Academia Sinica, Taiwan (www.ibc.sinica.edu.tw) seeks outstanding candidates to fill tenure-track faculty positions. While our primary focus is on hiring at the Assistant Research Fellow level, we also welcome applications from more experienced candidates, including those at the Research Fellow level. The Institute has a long tradition of excellence in research at the biology/chemistry interface, in particular protein biochemistry, structural biology, glycoscience and the study of other post-translational modifications. In this search, we are seeking candidates whose research interests complement existing research programs in the Institute. Individuals with expertise in quantitative or computational biology who are able to address the dynamics and complexity of biochemical problems are of particular interest. Experience integrating AI-based technologies into research projects is also highly desired. However, candidates with any relevant research programs will be considered. The chosen candidates will receive an appointment at the Institute of Biochemical Sciences, National Taiwan University (ibs.ntu.edu.tw), along with substantial start-up funds, ongoing intramural support, and full access to all shared resources in Academia Sinica. Application materials should include: 1) A cover letter with the names of three referees who will write on the applicant’s behalf; 2) A curriculum vitae; 3) A statement of research accomplishments; and 4) A proposal for future research. Application materials should be combined into a single PDF file and sent to the Chair of Recruitment Committee, c/o Ms. Pei-Ru Liao (email: prliao@gate.sinica.edu.tw). The applicant should arrange for the letters from the three referees to be sent directly to prliao@gate.sinica.edu.tw. Screening of applications will begin on September 1, 2025 and will continue until the positions are filled.

IBC is dedicated to fostering a diverse and inclusive workforce, and we actively encourage applications from individuals of all backgrounds. We particularly welcome applications from women, indigenous peoples, individuals from visible minority groups, persons with disabilities, and those of any sexual orientation or gender identity. Proficiency in Mandarin Chinese is not a prerequisite for application.

【Research Focus】
The Lab for Cell Dynamics (LCD) at Academia Sinica explores the biological functions of large-scale cell death during embryonic development, integrating advanced quantitative and imaging techniques. Our recent work (PMID: 38987590) reveals how developmental signals prime cells for death and how this process might influence aging. We invite passionate junior scientists to join our team to investigate:
1.How developmental cues orchestrate cell death during development.
2.The potential link between developmental death signaling and the aging process.

研究聚焦於離線RL(Reinforcement Learning)、穩健性RL模型，以及在金融與機器人等真實場域的應用。

主要職責
- 進行 RL 相關研究
- 主導或參與頂尖國際會議／期刊投稿
- 協助撰寫研究計畫並推動產學合作
We seek a highly motivated postdoctoral researcher who wants to push the frontier of sequential decision-making under uncertainty and deploy results in impactful domains.

- Conduct independent and collaborative research on RL
- Co-supervise graduate students and research assistants
- Lead or contribute to top-tier conference/journal submissions
- Assist with grant writing and industry collaborations

本實驗室致力於運用分子生物學的方法，研究快速演化的基因與染色體結構。我們對於具有重要功能的基因與染色體結構在演化上理應高度保守，卻仍觀察到快速演化的現象感到好奇，並希望進一步理解背後的機制與演化動力。我們目前的研究發現自私的基因可以解釋部分這些現象。我們的研究將針對這些矛盾現象進行系統性探討，並結合不同層次的實驗方法深入剖析其生物學意涵。 本實驗室將於 2025 年 10 月正式成立，現誠徵博士後助理新實驗室進行主導，並發展獨立研究計畫，並有機會參與論文發表並獲得作者資格。我將會視情況提供參與國際研討會或參與國外合作者實驗室的機會。我將提供職涯發展的建議及協助。 工作內容： -主導獨立規劃並執行研究計畫 -撰寫論文並協助申請研究計劃 -鼓勵發展獨立研究計劃 -帶領並指導年輕實驗室成員 -參與實驗室會議並定期報告研究進度 -每週更新實驗進展

My lab at the Institute of Molecular Biology (IMB), Academia Sinica, focuses on the rapid evolution of essential genes and chromosome structures. We are particularly interested in the paradox of how genes and chromosomal features critical for survival and reproduction, typically expected to be evolutionarily conserved, can instead evolve rapidly under strong positive selection. To investigate this, we integrate genetics, genomics, and cytology to uncover the causes and consequences of this phenomenon.

We are seeking 1 postdoctoral researcher to conduct and lead research projects. Candidates will earn authorship on resulting publications and will be strongly encouraged to develop and lead independent projects. Successful candidates will have opportunities to attend international conferences and visit collaborator labs in US or Canada. I’m strongly committed to supporting career development and mentorship for all team members.

Responsibilities:

Lead and contribute to research projects, including international collaborations
Draft and revise manuscripts for publication; assist in grant writing
Develop and pursue independent research directions
Mentor junior lab members
Present data at lab meetings and provide regular project updates
Maintain weekly progress reports on experiments and analysis

Responsibilities for postdoctoral fellow:
• Leading independent research, design and carrying out well controlled, reproducible experiments which address well-developed hypotheses.
• Work closely with other team members and external collaborators.
• Present progress internally and externally through conferences.
• Writing manuscripts and assisting with grant applications.

Responsibilities for research assistant:
• Collaborating with team members to design and establish various biochemical assays, molecular biological techniques, mouse colony management and assist mouse-based experimental techniques when needed.
• Overseeing day-to-day lab operations, provide administrative support, maintenance of safety standards, restock and purchasing, databases and standard operating procedures, and general organization of the lab.

The Cheung Lab, relocating from the Francis Crick Institute (London, UK) to the Genomics Research Center (GRC), Academia Sinica (Taipei) in August 2025, is seeking highly motivated and creative researchers to join our team. In GRC, you will be joining a group of enthusiastic postdocs and PhD students with diverse expertise in cancer research and metabolism and will have access to state-of-the-art approaches and resources in GRC as well as other AS institutes.

Our goal is to understand how cancer cells communicate with their immediate microenvironment as well as distal host tissues and organs to regulate metabolic stress and redox homeostasis in tumours to facilitate growth and metastasis, focusing on pancreatic cancer (Cheung et al. PNAS 2024, Cheung and Vousden Nat Rev Cancer 2022, Cheung et al. Cancer Cell 2020, Cheung et al. Genes Dev 2016, Cheung et al. Developmental Cell 2013). We employ functional genomics, metabolomics, ex vivo organoid models, animal models of cancer, and single cell sequencing to uncover new mechanisms of disease and therapeutic targets. Our work seeks to reveal novel strategies that target both cancer cells and host tissues, offering a more refined, systemic approach to cancer treatment.

Research Associate Positions at IMB, Academia Sinica (Starting October 2025)
My lab at the Institute of Molecular Biology (IMB), Academia Sinica, focuses on the rapid evolution of essential genes and chromosome structures. We are particularly interested in the paradox of how genes and chromosomal features critical for survival and reproduction, typically expected to be evolutionarily conserved, can instead evolve rapidly under strong positive selection. To investigate this, we integrate genetics, genomics, and cytology to uncover the causes and consequences of this phenomenon.
We are seeking 1–2 highly motivated B.S. or M.S.-level research associates to join the lab and contribute to new and ongoing projects. Successful candidates will have opportunities to co-author publications and are encouraged to lead independent research projects. Based on performance, there will be opportunities to attend international conferences and visit collaborating labs in the U.S. or Canada. I am committed to supporting career development and mentorship for all team members.

Responsibilities:
•Perform basic molecular biology experiments:
oPCR, molecular cloning, DNA and RNA extraction, sequencing
•Assist with lab management:
oMedia preparation, ordering supplies, and equipment maintenance
•Take initiative to lead or contribute to research projects
•Present work in lab meetings and provide weekly updates

ASIAA CASA Development Center (ACDC) is a software team for the ALMA-Taiwan project, focusing on quality software development to boost science productivity. Please check https://cartavis.org to see what we are actively working on. We are looking for one software developer and one computing system manager with enthusiasm and interests in astronomy to join our team.

【Position description】
The Institute of Statistical Science, Academia Sinica, invites applications for tenure-track positions at the levels of Assistant, Associate, or Full Research Fellow (equivalent to Assistant, Associate, or Full Professor at universities). We seek visionary researchers eager to contribute to our interdisciplinary community. Candidates should bring fresh perspectives to statistics, data science, and related fields such as computer science and artificial intelligence.

【Job description】
Academia Sinica, Taiwan’s most preeminent academic research institution, offers generous research funding, travel support, faculty housing, and other benefits. The Institute of Statistical Science provides a secure and stimulating research environment, with more than 30 faculty members, supportive administrative and IT teams, and many international visiting scholars and academic activities annually. Unlike university faculty, our researchers have the flexibility to choose whether or not to teach.

Launched in September 2022, the Kamino Lab investigates the fundamental principles that govern cellular behavior and information processing. With Keita’s background in physics, our lab integrates diverse approaches, including molecular genetics, theoretical physics, microscopy, and machine learning. We are currently seeking two research assistants with strong backgrounds in related fields and a passion for interdisciplinary research. Potential areas of exploration include, but are not limited to:
- Live-cell analysis of cellular behaviors using advanced microscopy techniques
- Theoretical analysis of cell-signaling dynamics using probability, information theory, and dynamical systems theory
- Image and time-series analysis using advanced statistical methods, including machine learning
- Development of cutting-edge measurement tools in microscopy and microfluidics