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The lab of Ka Wai Ma is inviting application working on a NSTC-
funded project titled Transcriptome-guided combinatorial gene
editing to understand plant-microbiota homeostasis. The Ma lab
uses both gnotobiotic Arabidopsis and the associated bacterial culture
collection to understand the principles governing plant-microbiota
homeostasis. Our research employs a multitude of omics techniques
including 16S amplicon sequencing, transcriptomics and proteomics
for functional analyses. The lab is currently looking for a motivated
candidate to work on a CRISPR editing project with subsequent
phenotyping.
The position is opened until filled
馬家威實驗室現誠聘研究助理/博士後，從事由國科會資助【以轉錄組
導向進行組合基因編輯以了解植物微生物相的平衡機理】項目。本實驗
室使用阿拉伯芥模型系統和相關的微生物庫進行植物微生物相重組實驗
以了解植物微生物群互動平衡機理。實驗室使用擴增子測序、轉錄組學
及肽組學分析等技術，並提供相關技術培訓。

【Research Focus】
The Lab for Cell Dynamics (LCD) investigates how cells make decisions—how they differentiate, survive, die, and interact during cancer development and embryogenesis. We combine cutting-edge, quantitative tools: single-cell time-lapse imaging, two-photon microscopy, mathematical modeling & simulation and big-data analysis.
Our model systems include cancer cells, stem cells, organoids, and model organisms (e.g., flies, zebrafish, mice). If you are interested in answering unknown and significant questions in biology, you will fit right in!

Two key projects:
1. How does cell death shape the embryos during development?
2. How normal and cancer cells respond to stress differently?

1. Design and engineering (assited with AI) of the fluorescent protein-based biosensors in bacteria (E. coli).
2. Purification (with His tag of E. coli-based recombinant proteins) and biochemical/biophysical characterization of the purified biosensors.
3. Live mammalian cell imaging with a fluorescence microscope at high spatial and temporal resolution.

1. Design and engineering (assited with AI) of the fluorescent protein-based biosensors in bacteria (E. coli).
2. Purification (with His tag of E. coli-based recombinant proteins) and biochemical/biophysical characterization of the purified biosensors.
3. Live mammalian cell imaging with a fluorescence microscope at high spatial and temporal resolution.
4. Administration works such as management of fund, schedule, travel, reimbursement.

My laboratory studies complex tissue regeneration using the zebrafish model. We seek highly-motivated colleagues with interests in regeneration, multicolor cell barcoding technique, live imaging, genetics, or working with zebrafish.

More information about the laboratory can be found at:
https://sites.google.com/view/chenlab-website/home
https://sites.google.com/view/chenlab-website/home/in-the-news

【About Sakamoto Lab】
What is Life? How do lifeless molecules come together to create dynamic and purposeful living things? Newly founded in September 2025, “Laboratory of Designer Life” explores this fundamental question from physics viewpoints by combining experiments and theory. We take a bottom-up approach: instead of studying living cells as they are, we re-build key aspects of life in the lab, piece by piece, using building blocks of life. Our goal is to reveal the core principles underlying the beautiful self-organization of life. We seek people who are motivated to work on:

1. Developing experimental systems integrating microfabrication and purified biomolecules to observe their self-organization
2. Experimental measurements using microscopes, quantitative image analysis, and theoretical analysis
3. Basic administration such as ordering/managing lab items, reimbursement, and scheduling

【Research Focus】
Potential areas of exploration include but are not limited to:

1. Biomolecular Self-Organization: Explore to understand how nm-scale biomolecules spontaneously assemble into µm-to-mm-scale larger functional structures without any blueprint by developing innovative bottom-up systems
2. Engineering Life: Designing and building life-like systems that not only mimic but could potentially outperform natural cells, which will open up exciting opportunities in biotechnology and sustainable material development

Please visit our website for more details: https://sites.google.com/as.edu.tw/sakamoto-lab

【What We Offer】
1. Innovative Environment: Work at the forefront of biophysics, active matter physics, bioengineering, and synthetic biology
2. Skill Development: Gain hands-on experience in advanced microfabrication and in vitro protein experimental techniques, scientific writing and presentation skills
3. Collaborative Culture: Join the team that is motivated to develop and share knowledge for mutual growth

1. 魚類族群生態資料分析、撰寫論文
2. 採集、整理魚類生物及環境因子資料
3. 支援實驗室一般行政事務
1. Analyze fish ecological datasets and write research papers
2. Collect and organize fish biological and environmental data
3. Support general laboratory administrative activities

工作內容：我們實驗室的研究主題為探討植物中mRNA遠距
運輸的分子機制。主要研究項目為利用活體細胞顯微技術、
蛋白質體學及分子遺傳學技術分析參與mRNA遠距運輸的關
鍵機制。

B細胞的發育分化與恆定，及其與疾病關聯性之研究。
使用人類檢體，基因剔除或轉殖小鼠動物模式實驗來研究B細胞功能，及於生理恆定與疾病進程所扮演之角色與分子機制。
起聘日：01/01/2026 起

Research and Work Content
• Research Focus: Research on B cell development, differentiation, and homeostasis, and their relationship with diseases.
• Job Description: Using human specimens , knockout or transgenic mouse models to study B cell function and the molecular mechanisms they play in physiological homeostasis and disease progression.
• Start Date: January 1, 2026

1. 協助維護及操作核心實驗室相關軟硬體及儀器設施。
2. 操作基因體技術研究相關實驗，包括RNA, DNA 的品質檢測分析，次世代定序 library 的製備等實驗操作。
3. 實驗室例行事務管理工作
4. 臨時交代事項

Our research team is seeking a Postdoctoral Researcher to join us in exploring the evolution, ecology, and biology of eukaryotic microbes with key ecological roles on Earth. We focus on the interactions between microbes and their environment and utilize cutting-edge omics and bioinformatics tools to uncover their evolutionary trajectories and regulatory mechanisms. Currently, we are conducting an NSTC-funded project on marine algae, population variation, and warming. This position is open until filled.

Research Topics
1. Population genomics and evolutionary biology of marine algae.
2. Effects of oceanographic and physico-chemical factors on algal distribution.
3. Genomic variation, transcriptomic regulation and physiological properties of lipid synthesis and host-virus interactions in marine algae.

Job description:
1. Lead and participate in research projects.
2. Design and conduct experiments or data analyses.
3. Establish standardized protocols or pipelines for all team members.
4. Actively participate in scientific writing and presentation
5. Mentor junior researchers

Our research team is seeking 1~2 Research Associates to join us in exploring the evolution, ecology, and biology of eukaryotic microbes with key ecological roles on Earth. We focus on the interactions between microbes and their environment and utilize cutting-edge omics and bioinformatics tools to uncover their evolutionary trajectories and regulatory mechanisms. Currently, we are conducting an NSTC-funded project on marine algae, population variation, and warming. This position is open until filled.

顧銓研究室現正招募 1 至 2 位研究助理，加入我們探索真核微生物之演化、生態與生物學上的關鍵生態角色。我們著重微生物與環境之間的互動，並利用尖端的多體學與生物資訊工具發掘演化軌跡與調控機制。目前我們正執行國科會(NSTC)資助的計畫，研究海藻族群變異與暖化相關議題。本職缺即日起開放申請，額滿為止。

Research Topics
1. Population genomics and evolutionary biology of marine algae.
2. Effects of oceanographic and physico-chemical factors on algal distribution.
3. Genomic variation, transcriptomic regulation and physiological properties of lipid synthesis and host-virus interactions in marine algae.

研究主題
1. 海洋微藻族群基因體學與演化生物學
2. 海洋科學及海洋物理化學因子對微藻分佈的影響
3. 海洋微藻基因體變異,、轉錄體調控、生理特性對脂質生合成機制影響 ，以及對宿主-病毒交互作用關係。


Job description (Tasks are assigned flexibly; not all are required.)
-Culture and maintain microalgal and protist strains.
-DNA/RNA extraction, NGS libraries preparation, and perform sequencing.
-Design and conduct genomic, transcriptomic, or metabolomics experiments and analyses.
-Perform bioinformatic analyses, including genome assembly, annotation, and phylogenomic analysis, etc..
-May participate in field sampling during research cruises.
-Manage routine laboratory tasks and other assigned duties.

工作內容（彈性分配，非所有項目皆為必須）
-培養與維護微藻與原生生物菌株
-DNA/RNA抽取、NGS library建置與定序
-設計並執行基因體、轉錄體或代謝體實驗與數據分析
-生物資料分析，包括基因體組裝、註解、系統基因組學分析等
-研究航次期間，可能需參與現場採樣
-實驗室例行管理與其他交辦事項