Academia Sinica Logo

The Lee lab at the Genomics Research Center (GRC), Academia Sinica in Taipei is seeking highly motivated and creative researchers at different levels to study metabolic biology and metabolism-related diseases. The Lee lab has a long-standing research interest in the crosstalk between immune and metabolic signaling, or immunometabolism, and its impact on physiological/pathophysiological processes. Examples of study areas include (but not limited to):
* Immunometabolism in tissue homeostasis (Science 368:eaat3987; J Clin Invest 123:261; Nat Med 18:1665)
* Mitochondrial dynamics in liver metabolism (JCI Insight 7:e150041; Cell Metab 22:709)
* Circadian/metabolic rhythm and metabolites mediated inter-organ communication (Nature 502:550)
* Mitochondrial bioenergetics in inflammatory activation and resolution of immune cells (eLife 9:e54090; Cell Metab 7:485

大氣雲模式及降水粒子運動數值模擬與分析
Perform numerical simulation and analysis of atmospheric cloud model and precipitation particle motions.

Our research team is seeking a Postdoctoral Researcher to join us in exploring the evolution, ecology, and biology of eukaryotic microbes with key ecological roles on Earth. We focus on the interactions between microbes and their environment and utilize cutting-edge omics and bioinformatics tools to uncover their evolutionary trajectories and regulatory mechanisms. Currently, we are conducting an NSTC-funded project on marine algae, population variation, and warming. This position is open until filled.

Research Topics
1. Population genomics and evolutionary biology of marine algae.
2. Effects of oceanographic and physico-chemical factors on algal distribution.
3. Genomic variation, transcriptomic regulation and physiological properties of lipid synthesis and host-virus interactions in marine algae.

Job description:
1. Lead and participate in research projects.
2. Design and conduct experiments or data analyses.
3. Establish standardized protocols or pipelines for all team members.
4. Actively participate in scientific writing and presentation
5. Mentor junior researchers

All position.
To conduct an innovative research program in computational (broadly-defined), materials, energy, catalysis, chemical biology or other chemistry areas.

We investigate the mechanisms of telomere maintenance in regulating aging and cancer development. We utilize cell biology, mouse models, and next-generation sequencing techniques to explore the role of telomere function in aging-related diseases and cancer. Additionally, by integrating clinical medicine and medicinal chemistry, we aim to understand disease mechanisms and develop therapeutic approaches.

【Research Focus】
The Lab for Cell Dynamics (LCD) at Academia Sinica explores the biological functions of large-scale cell death during embryonic development, integrating advanced quantitative and imaging techniques. Our recent work (PMID: 38987590) reveals how developmental signals prime cells for death. We invite passionate junior scientists to join our team to investigate: How developmental cues orchestrate cell death during development.

我們正在尋找經驗豐富的行動應用程式開發人員，協助將 PQConnect 專案帶入 Android 和 iOS 作業系統。PQConnect 是一個全新且易於安裝的網路安全層，它能在有運行 PQConnect 的終端之間自動引入端到端的後量子加密技術。同時，它能與採用傳統密碼學的應用程式共同運作，並為任何已經內建後量子加密技術的使用者應用程式額外增加第二層的防護。PQConnect 在網路層的運作方式類似於 VPN，但它可容許的擴展性是大多數 VPN 應用程式所無法比擬的。如需了解更多資訊，請參考： https://www.pqconnect.net

【Research Focus】
The Lab for Cell Dynamics (LCD) at Academia Sinica explores the biological functions of large-scale cell death during embryonic development, integrating advanced quantitative and imaging techniques. Our recent work (PMID: 38987590) reveals how developmental signals prime cells for death and how this process might influence aging. We invite passionate junior scientists to join our team to investigate:
1.How developmental cues orchestrate cell death during development.
2.The potential link between developmental death signaling and the aging process.

1. 暖化對魚類生活史的影響 Effects of warming on fish life-histories
2. 暖化下的魚類族群動態 Effects of warming on fish population dynamics

研究聚焦於離線RL(Reinforcement Learning)、穩健性RL模型，以及在金融與機器人等真實場域的應用。

主要職責
- 進行 RL 相關研究
- 主導或參與頂尖國際會議／期刊投稿
- 協助撰寫研究計畫並推動產學合作
We seek a highly motivated postdoctoral researcher who wants to push the frontier of sequential decision-making under uncertainty and deploy results in impactful domains.

- Conduct independent and collaborative research on RL
- Co-supervise graduate students and research assistants
- Lead or contribute to top-tier conference/journal submissions
- Assist with grant writing and industry collaborations

本實驗室致力於運用分子生物學的方法，研究快速演化的基因與染色體結構。我們對於具有重要功能的基因與染色體結構在演化上理應高度保守，卻仍觀察到快速演化的現象感到好奇，並希望進一步理解背後的機制與演化動力。我們目前的研究發現自私的基因可以解釋部分這些現象。我們的研究將針對這些矛盾現象進行系統性探討，並結合不同層次的實驗方法深入剖析其生物學意涵。 本實驗室將於 2025 年 10 月正式成立，現誠徵博士後助理新實驗室進行主導，並發展獨立研究計畫，並有機會參與論文發表並獲得作者資格。我將會視情況提供參與國際研討會或參與國外合作者實驗室的機會。我將提供職涯發展的建議及協助。 工作內容： -主導獨立規劃並執行研究計畫 -撰寫論文並協助申請研究計劃 -鼓勵發展獨立研究計劃 -帶領並指導年輕實驗室成員 -參與實驗室會議並定期報告研究進度 -每週更新實驗進展

My lab at the Institute of Molecular Biology (IMB), Academia Sinica, focuses on the rapid evolution of essential genes and chromosome structures. We are particularly interested in the paradox of how genes and chromosomal features critical for survival and reproduction, typically expected to be evolutionarily conserved, can instead evolve rapidly under strong positive selection. To investigate this, we integrate genetics, genomics, and cytology to uncover the causes and consequences of this phenomenon.

We are seeking 1 postdoctoral researcher to conduct and lead research projects. Candidates will earn authorship on resulting publications and will be strongly encouraged to develop and lead independent projects. Successful candidates will have opportunities to attend international conferences and visit collaborator labs in US or Canada. I’m strongly committed to supporting career development and mentorship for all team members.

Responsibilities:

Lead and contribute to research projects, including international collaborations
Draft and revise manuscripts for publication; assist in grant writing
Develop and pursue independent research directions
Mentor junior lab members
Present data at lab meetings and provide regular project updates
Maintain weekly progress reports on experiments and analysis