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The major research interests in the LAI lab are to understand the molecular mechanisms underlying how bacterial pathogens deploy protein secretion systems for survival at its ecological niche and successful infection inside the plant host. We study the mechanistic and biological insights of the two major protein secretion nanomachines, type IV and type VI secretion systems (T4SS and T6SS), in Agrobacterium tumefaciens, the causal agent of crown gall disease and powerful gene transfer tool. We also aim to identify novel agrobacterial and plant genes critical for plant transformation and gene editing. The knowledge may provide new insights to improve Agrobacterium-mediated plant transformation and translational applications in biomedicine and/or agriculture.

The postdoc will carry out a two-year research grant to study the antibacterial T6SS with focuses to investigate the T6SS evolution and assembly mechanisms.

The LAI lab provides the research environments and expertise on studies of protein secretion and pathogen-plant interactions using various tools including genetics/genomics, molecular biology, biochemistry/proteomics, and cell biology. The research may expand to study structural aspects of T6SS-assocaited protein complex using X-ray crystallography and cryoEM. The postdoc is also encouraged to develop an independent project and will be trained to serve as a mentor toward an independent investigator. The LAI lab is also active in international collaborations, which will bring opportunities for abroad training.

The major research interests in the LAI lab are to understand the molecular mechanisms underlying how bacterial pathogens deploy protein secretion systems for survival at its ecological niche and successful infection inside the plant host. We study the mechanistic and biological insights of the two major protein secretion nanomachines, type IV and type VI secretion systems (T4SS and T6SS), in Agrobacterium tumefaciens, the causal agent of crown gall disease and powerful gene transfer tool. We also aim to identify novel agrobacterial and plant genes critical for plant transformation and gene editing. The knowledge may provide new insights to improve Agrobacterium-mediated plant transformation and translational applications in biomedicine and/or agriculture.

The Research Assistant will work with a senior Ph.D. student or a postdoc to carry out a two-year research grant to study the antibacterial T6SS with focuses to investigate the T6SS evolution and assembly mechanisms.

The LAI lab provides the research environments and expertise on studies of protein secretion and pathogen-plant interactions using various tools including genetics/genomics, molecular biology, biochemistry/proteomics, and cell biology. The research may expand to study structural aspects of T6SS-assocaited protein complex using X-ray crystallography and cryoEM. The postdoc is also encouraged to develop an independent project and will be trained to serve as a mentor toward an independent investigator. The LAI lab is also active in international collaborations, which will bring opportunities for abroad training.

針對臺灣地區一般民眾，執行臺灣人體生物資料庫計畫大台北地區宣導及收案作業。
工作內容包括：計畫宣導、問卷訪談、身體檢測、抽血與檢體處理等。

- Assist in studies of neuronal development,
synaptic plasticity, and mechanisms underlying
learning, memory, or sensory functions.
- Depending on expertise and interest, tasks may
include: cell biology, basic biochemistry, imaging,
data analysis, electrophysiology, or mouse
behavioral experiments.
- Support general laboratory operations and
management.

【Position description】
The Institute of Statistical Science of Academia Sinica is seeking visionary scientists to join our interdisciplinary research community. Applications are invited for tenure-track appointments as Full/Associate/Assistant Research Fellows (equivalent to Full/Associate/Assistant Professors in Universities). This tenure-track faculty position expects candidates to have new insights into statistics, data sciences, and computer science-related fields, including artificial intelligence.

【Job description】
Academia Sinica, Taiwan's most preeminent academic research institution, offers generous research funding, travel support, faculty housing, and other benefits. The Institute of Statistical Science provides a secure and stimulating research environment, with more than 30 faculty members, supportive administrative and IT teams, and many international visiting scholars annually. Unlike the universities, our faculty members have the freedom to choose to teach or not to teach.

1.研究助理：協助研究或獨立研究。
Research Assistants: Assist in research-related tasks or work on an independent project.
2.博士後研究員：表觀遺傳與轉錄調控於發育及疾病之角色。
Postdoctoral Fellows: Conduct research on the roles of epigenetics and transcriptional regulation in development and diseases.

The applicant should specialize at least one of the following fields: (1) GeoAI; (2) Geo-Computing; (3) Computational Social Science; or, (4) Geographic Information Science related research.

Highly desirable:
• Metabolomics: Proficiency in Mass Spectrometry or NMR-based metabolic profiling and analysis.
• Systemic Interaction: Experience in studying the Immune System or the Nervous System.
• Expertise in designing and executing complex in vivo experiments. A strong background in developing, breeding, and analyzing genetically modified animal models applied to cancer biology or neuroscience.

一、徵才說明
應用科學研究中心轄下之綠色科技專題中心，專注於奈米科學與工程技術的創新，致力於將基礎理論轉化為實際應用，以因應能源與環境挑戰。現誠徵對能源材料、奈米科技、永續工程具熱忱的研究人員加入，共同推動跨領域創新研究。
________________________________________
二、重點研究領域
1. 新能源科技：探索和發展新穎的能源技術，推動可再生能源的普及。
2. 儲能、產能與節能技術：開發高效能的儲能系統、提升能源產出效率並推動節能技術。
3. 奈米與裝置於永續能源之應用：運用奈米技術於能源裝置中，提升能源轉換效率，推動綠色科技的進步。
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三、加分條件
- 具備再生能源、儲能材料或能源轉換系統相關研發經驗。
- 熟悉奈米材料合成、微奈米製程技術或其在能源裝置上的應用。
- 有操作或設計儲能裝置或能量轉換系統經驗者佳。
- 具跨領域整合能力，如結合材料、裝置與AI數據分析優化設計。
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四、注意事項
- 即日起受理申請。
- 首聘為五年，聘任依本院「研究人員新聘、續聘、升等及特聘審議作業要點」辦理。
- 依條件提供研究經費及差旅補助。

- Employment Terms: Initial appointment is for five years, conducted in accordance with Academia Sinica's regulations for the recruitment, reappointment, promotion, and appointment of research personnel.
- Location: No. 28, Lane 70, Section 2, Academia Road, Nangang District, Taipei City.
- Benefits: Research funding and travel subsidies are provided based on eligibility and conditions.

一、徵才說明
應用科學研究中心轄下之量子光電專題中心，致力於開發光量子技術的關鍵材料與元件，推動量子科技在量子電腦、量子通訊與量子感測等應用領域的實現。現誠徵對量子光學、光電材料、量測技術與量子資訊應用具高度熱忱之研究人員加入，共同推動光子與量子科技的創新突破。
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二、重點研究領域
1. 量子光源與單光子偵測器之材料與元件技術開發。
2. 新型態量子光電元件研發。
3. 應用於量子電腦、量子通訊與量子感測的材料、元件與光量子技術。
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三、加分條件
- 曾參與量子光源或單光子偵測器之開發經驗。
- 熟悉量子材料製備與操控技術。
- 具備低溫光學量測、時間相關單光子計數系統或光子
- 有設計或製作新型態量子光電元件的經驗。
________________________________________
四、注意事項
- 即日起受理申請。
- 首聘為五年，聘任依本院「研究人員新聘、續聘、升等及特聘審議作業要點」辦理。
- 依條件提供研究經費及差旅補助。


- Employment Terms: Initial appointment is for five years, conducted in accordance with Academia Sinica's regulations for the recruitment, reappointment, promotion, and appointment of research personnel.
- Location: No. 28, Lane 70, Section 2, Academia Road, Nangang District, Taipei City.
- Benefits: Research funding and travel subsidies are provided based on eligibility and conditions.

一、徵才說明
應用科學研究中心轄下之智慧生物工程專題中心，致力於結合感測、成像、表徵量測與製造技術，推動生物醫學應用的新方向。現誠徵對此領域具熱忱的研究人員加入，共同推動跨領域創新研究。
________________________________________
二、重點研究領域
1. 結合人工智慧開發先進生物感測或影像技術。
2. 新穎生物製造技術。
3. 微環境操控平台開發。
4. 臨床與生技產業應用之轉譯研究。
________________________________________
三、加分條件
- 具備穿戴式感測裝置、生物影像系統或智慧醫療相關技術之研發經驗。
- 熟悉感測器整合、資料同步處理、AI模型訓練與分析等跨域技術。
- 有參與生醫製造或微環境模擬平台開發者優先。
________________________________________
四、注意事項
- 即日起受理申請。
- 首聘為五年，聘任依本院「研究人員新聘、續聘、升等及特聘審議作業要點」辦理。
- 依條件提供研究經費及差旅補助。


- Employment Terms: Initial appointment is for five years, conducted in accordance with Academia Sinica's regulations for the recruitment, reappointment, promotion, and appointment of research personnel.
- Location: No. 28, Lane 70, Section 2, Academia Road, Nangang District, Taipei City.
- Benefits: Research funding and travel subsidies are provided based on eligibility and conditions.

Using mouse models and human iPSC system, together with scRNA/ATAC-seq technique to decipher the molecular mechanism for Neurodegeneration and Aging. We also aim to uncover the new method to cure motor neuron disease by gene therapy. We strongly encourage candidates interested in molecular mechanisms of gene regulation as related to non coding RNAs should apply. Candidates experienced in mouse experiments and ESC/iPSC cell culture are preferred, but not required.