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Some vertebrate animals, such as zebrafish and salamanders, can heal large cutaneous wounds within hours. Investigating this process may reveal new approaches in regenerative medicine. Dr. Chen-Hui Chen at the Institute of Cellular and Organismic Biology (ICOB), along with Dr. Ji-Yen Cheng at the Research Center for Applied Sciences (RCAS), and their teams have developed a macroscopic live imaging platform capable of capturing approximately 60,000 Superficial Epithelial Cells (SECs) within a single field of view. They found that fin-resident epithelial cells are highly mobile, migrating to cover nearby millimeter-sized body wounds. They propose that fin tissues or vertebrate appendages may act as a massive reservoir of healing cells, speeding up wound closure and tissue repair. This unexpected finding was published in July this year in the journal Current Biology. The first author, Fiorency Santoso, is a research assistant in Dr. Chen's laboratory. Other team members include Marco De Leon, Wei-Chen Kao, Wei-Chen Chu, Hsiao-Yuh Roan, Gang-Hui Lee, Ming-Jer Tang, Ji-Yen Cheng, and Chen-Hui Chen. This study is supported by funding from the Institute of Cellular and Organismic Biology and grants from Academia Sinica and the National Science and Technology Council, Taiwan, to C.-H.C.