Distinguished Research Fellow Dr. Patrick C.H. Hsieh’s team at the Institute of Biomedical Sciences, Academia Sinica uncovered a pivotal gut-heart axis in post-myocardial infarction (MI) cardiac repair. Employing human clinical samples, nonhuman primate disease models, and mouse cardiac injury models, they revealed the significance of butyrate-producing bacteria, particularly in synthesizing β-hydroxybutyrate post-injury. This breakthrough offers precision medication targets for MI through gut microbiota adjustments. The study, titled "Gut Butyrate-Producers Confer Post-Infarction Cardiac Protection," published in Nature Communications on November 9, involved collaborators from National Cheng Kung University, China Medical University Hospital, Far Eastern Memorial Hospital, and the University of Wisconsin-Madison (UW-Madison).