HomeDate: 2026-03-26
Speaker: Prof. Kurt Wüthrich (2002 Nobel Laureate in Chemistry)
Host: Dr. James C. Liao, President of Academia Sinica
Time: April 7, 2026, Tuesday, 14:00
Venue: International Conference Hall (3F), Humanities and Social
Sciences Building, Academia Sinica
Online Registration https://forms.gle/nCazxi6XujU9VzY1A
Government employees participating in the lecture will receive
certification for lifelong learning and 2 hours of study credit.
Contact:Mr. Chang, Department of International Affairs, Academia Sinica
Tel: (02) 2789-9895
Lecture Synopsis:
In my lecture, I will survey the physiological roles of three important classes of biological macromolecules, DNA, RNA and Proteins. In the introduction I will emphasize the importance of knowledge about the three-dimensional structures of these molecules, in addition to their
chemical structure. In this context I will briefly describe the principal methods available for experimental determination of three-dimensional structures of these macromolecules, X-ray crystallography, NMR spectroscopy and cryo-EM. I will then link the recent success of
structure prediction by methods of artificial intelligence with the experimental approaches to structure determination, and discuss the impact of the wealth of information on macromolecular structures on drug development for the continued improvement of human healthcare.
