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我們正在積極招募對染色質生物學、基因調控與功能性基因體學有興趣的研究助理加入團隊。理想的候選人應具備良好的組織能力，並樂於在合作型研究環境中工作。
我們研究疾病相關的染色質調控因子與組蛋白突變如何擾亂基因調控機制。研究助理將協助進行相關研究計畫，包括基本分子生物學操作、基因克隆與哺乳類細胞培養，並有機會學習CRISPR 為基礎的突變分析與基因體學相關技術。

1.大樓機電等設施維護管理。
2.公務車輛管理。
3.清潔人力管理。
4.其他交辦事項。

Overview
We are seeking 1–2 postdoctoral fellows to join our lab in studying polymicrobial
interactions and host–microbe interactions with agricultural relevance. Our research
integrates comparative genomics, ecological sampling, microbial genetics, and
functional assays to understand how fungi, bacteria, and phages interact within
polymicrobial communities and how these interactions influence microbial pathogenesis
in plant hosts.
Our lab has strong expertise in functional genomics and experimental evolution, using
bottom-up approaches to address these questions. We welcome postdoctoral
researchers with complementary interests—such as plant immunity, evolutionary
genomics, or microbial ecology—to join our team. This position is ideal for recently
graduated PhD scientists who are passionate about microbial interactions and aspire to
pursue a faculty position in academia.
The position is open until filled.
Lab website: www.labofpie.org
Research Topics
1. Genetic basis of fungal–bacterial–phage interactions and their impact on
microbial community development
2. Comparative analysis of microbial pathogenic genes in single versus mixed
infections
3. Bioinformatic and evolutionary analysis of antimicrobial genes in plant pathogens
Job Responsibilities
1. Lead and contribute to independent and collaborative research projects
2. Design and conduct experiments and/or computational data analyses
3. Develop and maintain standardized laboratory protocols or bioinformatic
pipelines
4. Actively participate in manuscript preparation and scientific presentations
5. Mentor graduate and undergraduate researchers

We are seeking 1-2 M.S.-level research associates to join us in dissecting the
mechanisms and consequences of fungal-bacterial competition. We focus on the
interaction between Pseudomonas species and fungal plant pathogens. Using
ecological, functional genomic, and genetic approaches, we aim to determine whether
bacterial defense mechanisms are specific or general against multiple fungi, and vice
versa. Check our lab website: www.labofpie.org
Research topics
1. Functional genomic investigation of fungal or bacterial defense genes
2. Ecology and sampling of Pseudomonas species and interacting fungi in the wild
3. Co-evolutionary consequences of competing fungi and bacteria
Job description:
1. Lead and execute a small-scale independent research project.
2. Present data at the lab meeting and provide weekly research updates
3. Participate in joint lab meetings and journal clubs

This position is ideal for someone who seeks graduate-level training and have strong
interest in microbial ecology and genetics. This position is open until filled

參與電腦視覺、人工智慧與機器學習相關研究，目前本實驗室的研究聚焦於開發deep learning架構與演算法在電腦視覺的應用。研究重點如下: (1) Generative Computer Vision Techniques; (2) Image and Video Anomaly Detection and Localization; (3) Computer Vision Techniques for 3D Point Clouds; (4) Video Action and Activity Recognition; (5) Multimodal/VL Foundation Models Inspired Computer Vision Techniques; (6) Self-Supervised Learning for Computer Vision Applications; (7) Deepfake Detection & Security; and (8) Federated Learning Algorithms and Optimization。

執行iPSC核心設施服務

支援iPSC核心設施內一般事務

幹細胞培養、鑑定、分化與細胞庫管理 (具iPSC/ES cells培養經驗佳)

實驗動物飼育管理及飼養設備清潔

實驗動物飼育管理

1. 執行重力波研究計畫中的鏡片鍍膜相關研究工作
2. 研究工作主軸：運用本所儀器設備作測量、並參與未來儀儀效能增強的研發項目，亦須至台灣半導體研究中心(Taiwan Semiconductor Research Institute) 參加操作訓練課程，完成後利用該中心設備、製作薄膜。
3. 前境：半導體製程與實作經驗，為國內高科技產業高度需求。此外，計畫連接上的重力波研究，為基礎科學前沿，可提供強實平台，往國內外研究所升學。
4. 可因個別需求、興趣，客製工作內容與指標

The Tsai laboratory is looking for highly motivated talents to help us unveil how RNA modifications impact RNA biology. Successful applicants may aid in the following potential projects:
- Elucidate how intracellular Adenosine metabolism may regulate RNA methylation rates, in turn impacting Neurodegeneration in Alzheimer's disease model systems, in a collaboration with Yijuang Chern, Yi-Shuian Huang and others. This project involve the development and adaptation of new RNA modification detection methods, which may utilize the latest in Nanopore direct RNA-seq, Illumina RNA-seq, UPLC-tandem mass spectrometry, as well as more traditional molecular biology techniques.
- Explore how RNA modifications on viral and small RNAs in mosquito and monkey samples may impact the zoonotic virus reservoir within these animals that may spread to humans, in collaboration with Shin-Ru Shih. This project mainly utilizes Nanopore direct RNA-seq, though may not be limited to this technique.
- Elucidate how RNA modifications facilitate the replication, gene expression, and antiviral factor avoidance of Hepatitis B virus. This is a curiosity driven project that is not tied to any specific technique.
- General Nanopore direct RNA-seq bioinformatics analysis in support of any of the above projects.

蔡松智實驗室徵求具高度研究熱忱的優秀人才，共同探索RNA小分子修飾（如甲基化）如何影響RNA功能。可能的研究計畫包含：
- 細胞內Adenosine濃度對RNA甲基化的影響，而此機制如何影響阿茲海默症相關的神經退化：本計畫為與陳儀莊、黃怡萱老師及相關團隊之合作計畫。研究內容包含開發與優化最新的RNA修飾檢測技術，可能採用 Nanopore direct RNA-seq、Illumina RNA定序、超高效液相層析串聯質譜儀（UPLC-MS/MS）以及傳統分子生物學技術。
- 蚊子與猴子樣本中病毒及small RNA 修飾之研究： 本計畫與施信如老師合作，探討 RNA 修飾如何影響這些動物宿主體內的人畜共通病毒以及其向人類傳播的潛力。研究技術以 Nanopore direct RNA-seq為主。
- B型肝炎病毒（HBV）之 RNA 修飾： 釐清 RNA修飾如何協助B型肝炎病毒的複製、基因表現與逃避抗病毒因子之機制。此計畫所需技術依實驗結果而定不限於特定實驗技術。
- 針對Nanopore direct RNA-seq之生物資訊分析（可能協助以上所有計畫）。

(1)負責熱危害與健康調適研究計畫執行及管理。
(2)支援環境健康微型感測器或空氣品質觀測相關研究活動。

1. 加入本實驗室成員， 將協助以下計畫：以分子生物學或代謝體探討植物小分子在Systemic Acquired Resistance扮演的角色。
2. 將會定期進行科學文獻研讀和研究成果會議。
3. 將協助實驗室行政或例行維護工作。
4. 加入後將受訓代謝體或蛋白質, 植病相關實驗操作。因實驗需求, 可能需要出差。