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AS-TIGP Presidential Fellowship Award Ceremony and Awardee’s Open Lecture

Date: 2024-04-16

Since 2020, the AS-TIGP Presidential Fellowship has selected awardees each year. To add to the honor, the AS-TIGP Presidential Fellowship Awardees Open Lecture has been held since last year (2023), allowing awardees to give public lectures on their research, and to allow their advisors and colleagues to share in the honor.

This year, Ms. Hannah Katrina Co from the Philippines has received the AS-TIGP Presidential Fellowship Award. Ms. Co is a sixth-year Ph.D. candidate in the TIGP Molecular and Cell Biology Program under the supervision of Assistant Research Fellow Dr. Sheng-hong Chen at the Institute of Molecular Biology. The Open Lecture was held on April 8, 2024, with the award certificate conferred by the President of Academia Sinica, Dr. James C. Liao. The lecture's topic was "Emergence of spatially-infinite cell death via trigger waves of reactive oxygen species," demonstrating that long-range transmission of cell death can be achieved by trigger waves of reactive oxygen species (ROS). Unlike simple diffusion, whereby a signal dissipates quickly in space, ROS self-regenerates and propagates over long distances. Chemical and genetic perturbations indicate a primary role of ROS feedback loops (iron-mediated Fenton reaction, NADPH oxidase signaling, and the glutathione synthesis pathway) in the occurrence and progression of these cell death trigger waves. The Award Ceremony and the Open Lecture attracted many TIGP students and faculty members.