by Swami Onkar Shivraj, Debasish Chattopadhya and Gurprit Grover

Journal of Data Science, v.5, no.2, 289-296

Abstract

In the natural history of Human Immunodeficiency Virus Type-1 (HIV-1) infection, many studies included the participants who were seropositive at time of enrollment. Estimation of the unknown times since exposure to HIV-1 in the prevalent cohorts is of primary importance for estimation of the incubation period of Acquired Immunodeficiency Syndrome (AIDS). To estimate incubation period of AIDS we used prior distribution of incubation times, based on a external data as suggested by Bacchetti and Jewell (1991, Biometrics, 47,947-960). In the present study, our estimate was nonparametric based on a method proposed by Wang, Jewell and Tsai (1986, Annals of Statistics, 14, 1597-1605).

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